Evidence map›Paper›PMID 38902654›Full record

ArticleBMC pulmonary medicine2024

Prevalence, clinical characteristics, and disease burden of chronic cough in Italy: a cross-sectional study.

Raffaele Antonelli Incalzi, Antonio De Vincentis, Vicky W Li, Ashley Martin, Danilo Di Laura, Eileen Fonseca, Helen Ding

Abstract read
In one paragraph

Article in BMC pulmonary medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raffaele Antonelli IncalziUniversità Campus Biomedico di Roma and Fondazione Policlinico Universitario Campus Bio-Medico, via Alvaro del Portillo, 200, 00128, Rome, Italy.
Antonio De VincentisUniversità Campus Biomedico di Roma and Fondazione Policlinico Universitario Campus Bio-Medico, via Alvaro del Portillo, 200, 00128, Rome, Italy.
Vicky W LiOracle Life Sciences, Seattle, WA, USA.
Ashley MartinOracle Life Sciences, Seattle, WA, USA.
Danilo Di LauraMSD Italia S.r.l., Rome, Italy.
Eileen FonsecaMerck & Co., Inc., Rahway, NJ, USA.
Helen DingMerck & Co., Inc., Rahway, NJ, USA. helen.ding@merck.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic cough has been associated with reduced health-related quality of life, negative impacts on sleep, work, and other daily activities, and increased use of health care resources. Little is known about the prevalence of chronic cough in Italy. In the present study we sought to estimate the prevalence of chronic cough in Italy, describe sociodemographic and clinical characteristics associated with chronic cough, and characterize the impact of chronic cough on overall health and wellness, work and other daily activities, and health care resource use.

methodsWe conducted a cross-sectional study to collect sociodemographic and health-related data from Italian residents who participated in the 2020 National Health and Wellness Survey (N = 10,026). To assess the characteristics and burden of chronic cough, adults who indicated that they had experienced chronic cough during the prior 12 months were compared with propensity score-matched controls without chronic cough.

resultsThe estimated weighted lifetime and 12-month prevalence of chronic cough were estimated as 9.2% and 6.3%, respectively. Compared with matched controls, respondents with chronic cough had significantly lower measures of overall physical and mental health (P < .001 for both comparisons), and significantly higher rates of anxiety, depression, and sleep disorders (P < .001 for all comparisons). Chronic cough was significantly associated with higher rates of impairment of work and other activities (P < .001 for all comparisons) in the past 7 days, any-cause emergency department visits and hospitalizations in the prior 6 months (P < .001 for both comparisons), and more visits to general and specialist health care providers (P < .001 for both comparisons) in the prior 6 months.

conclusionsIn Italy, chronic cough affects an estimated 3.3 million adults annually and represents a significant burden to individuals and the health care system. TAKE HOME MESSAGE: Little is known about the prevalence of chronic cough in Italy. We found that, in Italy chronic cough represents a significant burden to individuals and the health care system, affecting an estimated 3.3 million adults annually.

Indexed as

Cost of IllnessCoughQuality of LifeActivities of Daily LivingAdolescentAdultAgedChronic CoughChronic DiseaseCross-Sectional StudiesFemaleHealth SurveysHumansItalyMaleMiddle AgedChronic coughChronic diseaseCoughHealth surveysItaly

Identifiers

PMID38902654
PMCPMC11191261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.