Evidence map›Paper›PMID 38902642›Full record

ArticleBMC public health2024

Impact of the 2008 economic crisis on the burden of hepatitis B and C diseases in Southern European countries.

Claudia Palladino, Rebeca Ramis, Ifeanyi Jude Ezeonwumelu, Antonio Biondi, Giulia Carreras, Florian Fischer, Silvano Gallus, Davide Golinelli, Giuseppe Gorini, Shoaib Hassan and 14 more

Abstract read
In one paragraph

Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Claudia PalladinoResearch Institute for Medicines, Faculty of Pharmacy, Universidade de Lisboa, Avenida Professor Gama Pinto, Lisbon, 1649-003, Portugal. cpalladino@edu.ulisboa.pt.
Rebeca RamisNacional Center for Epidemiology, Institute of Health Carlos III, Madrid, Spain.
Ifeanyi Jude EzeonwumeluInstitute for Health Science Research Germans Trias I Pujol, Autonomous University of Barcelona, Badalona, Spain.
Antonio BiondiDepartment of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy.
Giulia CarrerasInstitute for Cancer Research, Prevention, and Clinical Network, Florence, Italy.
Florian FischerInstitute of Public Health, Charité Universitätsmedizin Berlin, Charité Medical University Berlin), Berlin, Germany.
Silvano GallusDepartment of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Milan, Mario, Italy.
Davide GolinelliDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Giuseppe GoriniOncological Network, Prevention and Research Institute, Institute for Cancer Research, Prevention, and Clinical Network, Florence, Italy.
Shoaib HassanCenter for International Health (CIH), University of Bergen, Bergen, Norway.
Zubair KabirSchool of Public Health, University College Cork, Cork, Ireland.
Ai KoyanagiSan Juan de Dios Sanitary Park, Barcelona, Spain.
Jeffrey V LazarusBarcelona Institute for Global Health, Barcelona, Spain.
Alexios-Fotios A MentisBGI-Shenzhen, Shenzhen, Guangdong, China.
Tuomo J MeretojaBreast Surgery Unit, Helsinki University Hospital, Helsinki, Finland.
Ali H MokdadInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Lorenzo MonastaClinical Epidemiology and Public Health Research Unit, Burlo Garofolo Institute for Maternal and Child Health, Trieste, Italy.
Francesk MulitaDepartment of Surgery, General University Hospital of Patras, Patras, Greece.
Maarten J PostmaUniversity Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Rafael Tabarés-SeisdedosDepartment of Medicine, University of Valencia, Valencia, Spain.
Arulmani ThiyagarajanClinical Epidemiology, Leibniz Institute for Prevention Research and Epidemiology, Bremen, Germany.
Nuno Taveira *University Institute "Egas Moniz", Monte da Caparica, Portugal.
Verónica Briz *Laboratory of Viral Hepatitis, National Center of Microbiology, Institute of Health Carlos III, Carretera Majadahonda-Pozuelo Km 2.2, 28220, Majadahonda, Madrid, Spain. veronica.briz@isciii.es.
GBD 2019 Southern Europe Hepatitis B & C Collaborators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe economic crisis that began in 2008 has severely affected Southern (Greece, Italy, Portugal, Spain) Western European (SWE) countries of Western Europe (WE) and may have affected ongoing efforts to eliminate viral hepatitis. This study was conducted to investigate the impact of the economic crisis on the burden of HBV and HCV disease.

methodsGlobal Burden of Diseases 2019 data were used to analyse the rates of epidemiological metrics of HBV and HCV acute and chronic infections in SWE and WE. Time series modelling was performed to quantify the impact of healthcare expenditure on the time trend of HBV and HCV disease burden in 2000-2019.

resultsDeclining trends in incidence and prevalence rates of acute HBV (aHBV) and chronic HBV were observed in SWE and WE, with the pace of decline being slower in the post-austerity period (2010-2019) and mortality due to HBV stabilised in SWE. Acute HCV (aHCV) metrics and chronic HCV incidence and mortality showed a stable trend in SWE and WE, whereas the prevalence of chronic HCV showed an oscillating trend, decreasing in WE in 2010-2019 (p < 0.001). Liver cancer due to both hepatitis infections showed a stagnant burden over time. An inverse association was observed between health expenditure and metrics of both acute and chronic HBV and HCV.

conclusionsEpidemiological metrics for HBV and HCV showed a slower pace of decline in the post-austerity period with better improvement for HBV, a stabilisation of mortality and a stagnant burden for liver cancer due to both hepatitis infections. The economic crisis of 2008 had a negative impact on the burden of hepatitis B and C. Elimination of HBV and HCV by 2030 will be a major challenge in the SWE countries.

Indexed as

Cost of IllnessEconomic RecessionHepatitis BEuropeFemaleGlobal Burden of DiseaseHealth ExpendituresHepatitis B, ChronicHepatitis CHepatitis C, ChronicHumansIncidenceMalePrevalenceChronic liver diseasesCirrhosisDrugsEconomic crisisEpidemiologyGlobal burden of diseaseHepatitis BHepatitis CLiver cancerSouthern European countries

Identifiers

PMID38902642
PMCPMC11188182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.