ArticleHuman genetics2024
R2ROC: an efficient method of comparing two or more correlated AUC from out-of-sample prediction using polygenic scores.
Article in Human genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Analyzing complex traits and diseases using GxE PRS: genotype-environment interaction in polygenic risk score models.Journal of human genetics · 2025Article
- Geriatric nutritional risk index and prognostic nutritional index improves predictive value of postoperative mortality: a large-scale retrospective cohort study.Perioperative medicine (London, England) · 2025Article
- Enabling reproducible type 1 diabetes polygenic risk scoring for clinical and translational applications.medRxiv : the preprint server for health sciences · 2025Article
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Authors and funding
3 authors.
Funding
Abstract
Polygenic risk scores (PRSs) enable early prediction of disease risk. Evaluating PRS performance for binary traits commonly relies on the area under the receiver operating characteristic curve (AUC). However, the widely used DeLong's method for comparative significance tests suffer from limitations, including computational time and the lack of a one-to-one mapping between test statistics based on AUC and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.