Evidence map›Paper›PMID 38902461›Full record

ArticleScientific reports2024

Electrical impedance tomography provides information of brain injury during total aortic arch replacement through its correlation with relative difference of neurological biomarkers.

Yitong Guo, Chen Yang, Wenjing Zhu, Rong Zhao, Kai Ren, Weixun Duan, Jincheng Liu, Jing Ma, Xiuming Chen, Benyuan Liu and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yitong Guo *Shaanxi Provincial Key Laboratory of Bioelectromagnetic Detection and Intelligent Perception, Department of Biomedical Engineering, Fourth Military Medical University, Xi'an, 710032, China.
Chen Yang *Department of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Wenjing Zhu *Shaanxi Provincial Key Laboratory of Bioelectromagnetic Detection and Intelligent Perception, Department of Biomedical Engineering, Fourth Military Medical University, Xi'an, 710032, China.
Rong ZhaoDepartment of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Kai RenDepartment of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Weixun DuanDepartment of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Jincheng LiuDepartment of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Jing MaShaanxi Provincial Key Laboratory of Bioelectromagnetic Detection and Intelligent Perception, Department of Biomedical Engineering, Fourth Military Medical University, Xi'an, 710032, China.
Xiuming ChenShaanxi Provincial Key Laboratory of Bioelectromagnetic Detection and Intelligent Perception, Department of Biomedical Engineering, Fourth Military Medical University, Xi'an, 710032, China.
Benyuan LiuShaanxi Provincial Key Laboratory of Bioelectromagnetic Detection and Intelligent Perception, Department of Biomedical Engineering, Fourth Military Medical University, Xi'an, 710032, China.
Canhua XuShaanxi Provincial Key Laboratory of Bioelectromagnetic Detection and Intelligent Perception, Department of Biomedical Engineering, Fourth Military Medical University, Xi'an, 710032, China.
Zhenxiao JinDepartment of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China. 13571921011@163.com.
Xuetao ShiShaanxi Provincial Key Laboratory of Bioelectromagnetic Detection and Intelligent Perception, Department of Biomedical Engineering, Fourth Military Medical University, Xi'an, 710032, China. shixuetao@fmmu.edu.cn.

Funding

Cross-integration project of Xijing Hospital XJZT24JC37Innovation Foundation for Doctor Dissertation of Northwestern Polytechnical University CX2023088Key Basic Research Projects of the Basic Strengthening Plan of the Science and Technology Committee 2019-JCJQ-ZD-115-00-02Key Research and Development Projects of the Science and Technology Committee 2022YFC2404803National Natural Science Foundation of China -General Program 82370273
6 · The paper itself

Abstract

Postoperative neurological dysfunction (PND) is one of the most common complications after a total aortic arch replacement (TAAR). Electrical impedance tomography (EIT) monitoring of cerebral hypoxia injury during TAAR is a promising technique for preventing the occurrence of PND. This study aimed to explore the feasibility of electrical impedance tomography (EIT) for warning of potential brain injury during total aortic arch replacement (TAAR) through building the correlation between EIT extracted parameters and variation of neurological biomarkers in serum. Patients with Stanford type A aortic dissection and requiring TAAR who were admitted between December 2021 to March 2022 were included. A 16-electrode EIT system was adopted to monitor each patient's cerebral impedance intraoperatively. Five parameters of EIT signals regarding to the hypothermic circulatory arrest (HCA) period were extracted. Meanwhile, concentration of four neurological biomarkers in serum were measured regarding to time before and right after surgery, 12 h, 24 h and 48 h after surgery. The correlation between EIT parameters and variation of serum biomarkers were analyzed. A total of 57 TAAR patients were recruited. The correlation between EIT parameters and variation of biomarkers were stronger for patients with postoperative neurological dysfunction (PND(+)) than those without postoperative neurological dysfunction (PND(-)) in general. Particularly, variation of S100B after surgery had significantly moderate correlation with two parameters regarding to the difference of impedance between left and right brain which were MRAI

Indexed as

Aorta, ThoracicBiomarkersBrain InjuriesElectric ImpedanceAdultAgedAortic DissectionFemaleHumansMaleMiddle AgedPostoperative ComplicationsTomographyBiomarkers

Identifiers

PMID38902461
PMCPMC11190256

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.