Evidence map›Paper›PMID 38902452›Full record

ArticlePediatric research2025

Language and sensory characteristics are reflected in voice-evoked responses in low birth weight children.

Yuko Yoshimura, Yusuke Mitani, Takashi Ikeda, Sanae Tanaka, Momoka Suda, Ken Yaoi, Chiaki Hasegawa, Kyung-Min An, Sumie Iwasaki, Hirokazu Kumazaki and 6 more

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Article in Pediatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Yuko YoshimuraInstitute of Human and Social Sciences, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.
Yusuke MitaniDepartment of Pediatrics, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8640, Japan. ped.yusuke@gmail.com.
Takashi IkedaResearch Center for Child Mental Development, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.
Sanae TanakaResearch Center for Child Mental Development, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.
Momoka SudaResearch Center for Child Mental Development, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, Shizuoka, 431-3192, Japan.
Ken YaoiResearch Center for Child Mental Development, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.
Chiaki HasegawaResearch Center for Child Mental Development, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.
Kyung-Min AnCentre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, B15 2TT, UK.
Sumie IwasakiResearch Center for Child Mental Development, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.
Hirokazu KumazakiDepartment of Future Psychiatric Medicine, Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8521, Japan.
Daisuke N SaitoDepartment of Psychology, Yasuda Women's University, 6-13-1 Kuyasu, Asaminami, Hiroshima, 731-0153, Japan.
Hidenobu OhtaDepartment of Occupational Therapy, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita, 010-8543, Japan.
Akiko AndoMaternity and Perinatal Care Center, Hokkaido University Hospital, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan.
Kazutoshi ChoMaternity and Perinatal Care Center, Hokkaido University Hospital, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan.
Mitsuru KikuchiDepartment of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Japan.
Taizo WadaDepartment of Pediatrics, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren born with very low birth weight (VLBW) are at higher risk for cognitive impairment, including language deficits and sensorimotor difficulties. Voice-evoked response (P1m), which has been suggested as a language development biomarker in young children, remains unexplored for its efficacy in VLBW children. Furthermore, the relation between P1m and sensory difficulties in VLBW children remains unclear.

methods40 children with VLBW were recruited at 5-to-6 years old (26 male, 14 female, mean age of months ± SD, 80.0 ± 4.9). We measured their voice-evoked brain response using child-customized magnetoencephalography (MEG) and examined the relation between P1m and language conceptual inference ability and sensory characteristics.

resultsThe final sample comprised 36 children (23 boys, 13 girls; ages 61-86 months; gestational ages 24-36 weeks). As a result of multiple regression analysis, voice-evoked P1m in the left hemisphere was correlated significantly with language ability (β = 0.414 P = 0.015) and sensory hypersensitivity (β = 0.471 P = 0.005).

conclusionOur findings indicate that the relation between P1m and language conceptual inference ability observed in term children in earlier studies is replicated in VLBW children, and suggests P1m intensity as a biomarker of sensory sensitivity characteristics. IMPACT: We investigated brain functions related to language development and sensory problems in very low birth-weight children. In very low birth weight children at early school age, brain responses to human voices are associated with language conceptual inference ability and sensory hypersensitivity. These findings promote a physiological understanding of both language development and sensory characteristics in very low birth weight children.

Indexed as

Infant, Very Low Birth WeightLanguageLanguage DevelopmentVoiceBrainChildChild, PreschoolFemaleHumansInfant, NewbornMagnetoencephalographyMale

Identifiers

PMID38902452
PMCPMC11798859

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.