Evidence map›Paper›PMID 38902222›Full record

Articlenpj aging2024

Increased vascular smooth muscle cell senescence in aneurysmal Fibulin-4 mutant mice.

Sanne J M Stefens, Nicole van Vliet, Arne IJpma, Joyce Burger, Yunlei Li, Paula M van Heijningen, Jan H N Lindeman, Danielle Majoor-Krakauer, Hence J M Verhagen, Roland Kanaar and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in npj aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. A Del(5PNAS nexus · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Investigation of the Causal Association Between Biological Aging Indicators and Vascular Disease Through Two-Sample Mendelian Randomization Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sanne J M StefensDepartment of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Nicole van VlietDepartment of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Arne IJpmaDepartment of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Joyce BurgerDepartment of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Yunlei LiDepartment of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0002-5697-1602
Paula M van HeijningenDepartment of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Jan H N LindemanDepartment of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Danielle Majoor-KrakauerDepartment of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Hence J M VerhagenDepartment of Vascular Surgery, Cardiovascular Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Roland KanaarDepartment of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Jeroen EssersDepartment of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands. j.essers@erasmusmc.nl.ORCID http://orcid.org/0000-0003-0605-7211
Ingrid van der PluijmDepartment of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands. i.vanderpluijm@erasmusmc.nl.ORCID http://orcid.org/0000-0002-9368-5779

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aortic aneurysms are dilatations of the aorta that can rupture when left untreated. We used the aneurysmal Fibulin-4

Identifiers

PMID38902222
PMCPMC11189919

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.