Evidence map›Paper›PMID 38901886›Full record

SynthesisThe European respiratory journal2024

Global herpes zoster burden in adults with asthma: a systematic review and meta-analysis.

Kevin J Mortimer, Alvaro A Cruz, Ingrid T Sepúlveda-Pachón, Anamaria Jorga, Hilde Vroling, Charles Williams

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in The European respiratory journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Global herpes zoster burden in adults with COPD: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Herpes Zoster in Aging Patients: Risk Factors and Prevention Strategies.International journal of general medicine · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Kevin J MortimerCambridge Africa, Department of Pathology, University of Cambridge, Cambridge, UK.
Alvaro A CruzProAR Foundation and Federal University of Bahia, Salvador, Brazil.
Ingrid T Sepúlveda-PachónP95 Epidemiology and Pharmacovigilance, Bogotá, Colombia.
Anamaria JorgaGSK, New York, NY, USA.
Hilde VrolingPallas Health Research and Consultancy, a P95 company, Rotterdam, The Netherlands.
Charles WilliamsGSK, Wavre, Belgium charles.t.williams@gsk.com.ORCID https://orcid.org/0000-0002-2437-3675

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAsthma is a common respiratory disease, which may be associated with an increased risk of herpes zoster (HZ), often a debilitating disease associated with severe pain. This is the first systematic review with the objective of summarising evidence on HZ burden in adults with asthma.

methodsA global systematic literature review and meta-analysis was conducted (MEDLINE and Embase, 2003-2024) on HZ burden (incidence, risk and complications) in adults (≥18 years) with asthma.

resultsThere were 19 studies included on HZ outcomes in adults with asthma. Pooled HZ incidence per 1000 person-years was 5.71 (95% CI 4.68-6.96) in adults aged ≥18 years (4.20 (95% CI 3.09-5.70) in those aged <60 years

conclusionsThis systematic literature review and meta-analysis found that adults with asthma have an increased risk of HZ, with higher risks in older age groups and in those on certain treatments, such as oral corticosteroids. HZ vaccines are available for adults, including those with comorbidities such as asthma, and can be considered as part of integrated respiratory care.

Indexed as

AsthmaHerpes ZosterAdrenal Cortex HormonesAdultGlobal HealthHumansIncidenceMiddle AgedRisk FactorsAdrenal Cortex Hormones

Identifiers

PMID38901886
PMCPMC11306804

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.