Evidence map›Paper›PMID 38900788›Full record

ArticlePLoS neglected tropical diseases2024

Inactivation of yellow fever virus by WHO-recommended hand rub formulations and surface disinfectants.

Toni Luise Meister, Nicola Frericks, Robin D V Kleinert, Estefanía Rodríguez, Joerg Steinmann, Daniel Todt, Richard J P Brown, Eike Steinmann

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Hantavirus stability and inactivation.PLoS neglected tropical diseases · 2026
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Toni Luise MeisterDepartment for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.ORCID 0000-0001-8962-9443
Nicola FrericksDepartment for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.
Robin D V KleinertDivision of Veterinary Medicine, Paul-Ehrlich-Institute, Langen, Germany.
Estefanía RodríguezGerman Centre for Infection Research (DZIF), Partner site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.
Joerg SteinmannInstitute of Clinical Hygiene, Medical Microbiology and Infectiology, General Hospital Nürnberg, Paracelsus Medical University, Nuremberg, Germany.
Daniel TodtDepartment for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.
Richard J P BrownDepartment for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.
Eike SteinmannDepartment for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.ORCID 0000-0002-3654-9965

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite continued outbreaks of yellow fever virus (YFV) in endemic regions, data on its environmental stability or guidelines for its effective inactivation is limited. Here, we evaluated the susceptibility of the YFV 17D vaccine strain to inactivation by ethanol, 2-propanol, World Health Organization (WHO)-recommended hand rub formulations I and II, as well as surface disinfectants. In addition, two pathogenic strains were tested to compare inactivation kinetics by WHO-recommended hand rub formulations I and II. Furthermore, environmental stability of the vaccine strain was assessed. YFV 17D particles displayed infectivity half-life decay profiles of ~13 days at room temperature. Despite this extended environmental stability, YFV was efficiently inactivated by alcohols, WHO-recommended hand formulations, and four out of five tested surface disinfectants. These results are useful in defining disinfection protocols to prevent non-vector borne YFV transmission.

Indexed as

DisinfectantsVirus InactivationWorld Health OrganizationYellow fever virusAnimalsChlorocebus aethiopsHand DisinfectionHumansYellow FeverDisinfectants

Identifiers

PMID38900788
PMCPMC11218936

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.