Evidence map›Paper›PMID 38900399›Full record

ArticleJournal of medical ultrasonics (2001)2024

Quantitative evaluation of lower limb varicose veins using photoacoustic imaging.

Moemi Urano, Kenichi Nagae, Sachiko Matsuda, Kentaro Matsubara, Takayuki Yagi, Nobuaki Imanishi, Sadakazu Aiso, Hideaki Obara, Masahiro Jinzaki

Abstract read
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In one paragraph

Article in Journal of medical ultrasonics (2001), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Moemi UranoDepartment of Radiology, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0003-1586-5237
Kenichi NagaeLuxonus Inc., Kawasaki, Kanagawa, Japan.
Sachiko MatsudaDepartment of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Kentaro MatsubaraDepartment of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Takayuki YagiLuxonus Inc., Kawasaki, Kanagawa, Japan.
Nobuaki ImanishiDepartment of Anatomy, Keio University School of Medicine, Tokyo, Japan.
Sadakazu AisoDepartment of Anatomy, Keio University School of Medicine, Tokyo, Japan.
Hideaki ObaraDepartment of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. obara.z3@keio.jp.
Masahiro JinzakiDepartment of Radiology, Keio University School of Medicine, Tokyo, Japan.

Funding

Japan Agency for Medical Research Development (AMED) JP19he2302002
6 · The paper itself

Abstract

purposeVaricose veins in the lower extremities are dilated subcutaneous varicose veins with a diameter of  ≥ 3 mm, caused by increased venous pressure resulting from backflow of blood due to venous valve insufficiency (Gloviczki in Handbook of venous disorders: guidelines of the American venous forum, Hodder Arnold, London, 2009). When diagnosing varicose veins, the shape and thickness of the blood vessels should be accurately visualized in three dimensions. In this study, we investigated a new method for numerical evaluation of vascular morphology related to varicose veins in the lower extremities, using a photoacoustic imaging (PAI) system, which can acquire high-resolution and three-dimensional images noninvasively.

methodsNine patients with varicose veins participated in the study, and their images were captured using an optical camera and PAI system. We visualized the vascular structure, created a blood presence density (BPD) heat map, and examined the correlation between BPD and location of varicose veins.

resultsThe obtained photoacoustic (PA) images demonstrated the ability of this method to visualize vessels ranging from as small as 0.2 mm in diameter to large, dilated vessels in three dimensions. Furthermore, the study revealed a correlation between the high-density part of the BPD heat map generated from the PAI images and the presence of varicose veins.

conclusionPAI is a promising technique for noninvasive and accurate diagnosis of varicose veins in the lower extremities. By providing valuable information on the morphology and hemodynamics of the varicose veins, PAI may facilitate their early detection and treatment.

Indexed as

Lower ExtremityPhotoacoustic TechniquesVaricose VeinsAdultAgedFemaleHumansImaging, Three-DimensionalMaleMiddle AgedBlood vesselHeat mapPhotoacoustic imagingVaricose vein

Identifiers

PMID38900399
PMCPMC11272806

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