Letter to the editor on: "Effect of different targets of goal-directed fluid therapy on intraoperative hypotension and fluid infusion in robot-assisted laparoscopic gynecological surgery: a randomized non-inferiority trial".

This study examined how different goal-directed fluid therapy types affected low blood pressure and fluid infusion during robot-assisted laparoscopic gynecological surgery. They used carotid corrected flow time (FTc) and tidal volume stimulation pulse pressure variation (VtPPV) to check the patient's volume status and responsiveness. The findings indicated that various fluid therapy targets significantly influence intraoperative hypotension and fluid requirements. However, the study exclusively employed unilateral carotid ultrasound assessments, potentially overlooking physiological or pathological variations in blood flow between the left and right carotid arteries. This methodological choice raises concerns as guidelines recommend bilateral measurements for a more comprehensive evaluation. The lack of bilateral assessments could affect the study's reliability and reproducibility. Justifying the unilateral measurement approach is essential for validating clinical findings. Future research should adopt bilateral carotid ultrasound assessments or provide a detailed rationale for unilateral measurements to enhance the robustness and accuracy of clinical evaluations.