Evidence map›Paper›PMID 38900326›Full record

ArticleAbdominal radiology (New York)2024

Unveiling the impact of cirrhotic cardiomyopathy on portal hemodynamics and survival after transjugular intrahepatic portosystemic shunt: a prospective study.

Yaozu Liu, Fangmin Meng, Jingqin Ma, Wen Zhang, Jiaze Yu, Yongjie Zhou, Wuxu Zuo, Zhiping Yan, Cuizhen Pan, Jianjun Luo

Abstract read
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In one paragraph

Article in Abdominal radiology (New York), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yaozu Liu *Shanghai Institution of Medical Imaging, Fudan University, Shanghai, China.
Fangmin Meng *Shanghai Institution of Medical Imaging, Fudan University, Shanghai, China.
Jingqin Ma *Shanghai Institution of Medical Imaging, Fudan University, Shanghai, China.
Wen ZhangShanghai Institution of Medical Imaging, Fudan University, Shanghai, China.
Jiaze YuShanghai Institution of Medical Imaging, Fudan University, Shanghai, China.
Yongjie ZhouShanghai Institution of Medical Imaging, Fudan University, Shanghai, China.
Wuxu ZuoShanghai Institution of Medical Imaging, Fudan University, Shanghai, China.
Zhiping YanShanghai Institution of Medical Imaging, Fudan University, Shanghai, China.
Cuizhen PanShanghai Institution of Medical Imaging, Fudan University, Shanghai, China. pan.cuizhen@zs-hospital.sh.cn.
Jianjun LuoShanghai Institution of Medical Imaging, Fudan University, Shanghai, China. luo.jianjun@zs-hospital.sh.cn.ORCID 0000-0003-4942-0439

Funding

Clinical research special fund from Zhongshan Hospital, Fudan University 2018ZSLC23Device development exploration project from National Clinical Research Center for Interventional Medicine 2021-001Excellent youth program from Zhongshan Hospital, Fudan University 2019ZSYXQN38National Natural Science Foundation of China 82302323Shanghai key clinical specialty construction program W2019028
6 · The paper itself

Abstract

BACKGROUND AND

aimsThe placement of Transjugular intrahepatic portosystemic shunt (TIPS) results in a sudden increase in central circulating blood volume, which requires proper regulation of the cardiovascular system. We aimed to investigate the impact of TIPS on cirrhotic cardiomyopathy (CCM).

methodA consecutive case series of patients with cirrhosis who underwent TIPS were evaluated by echocardiography and pressure measurements before, immediately after TIPS and 2-4 days later (delayed). Furthermore, all patients underwent a one-year follow-up.

resultsIn this study, 107 patients were enrolled, 38 (35.5%) with CCM. Echocardiography revealed an increase in postoperative left ventricular filling pressure accompanied by an elevation in left ventricular ejection fraction (LVEF). However, patients in the CCM group exhibited lower LVEF and mean arterial pressure (MAP) compared to the non-CCM group. Post-TIPS, CCM patients showed increased right atrium pressure (RAP) that normalized within 2-4 days, whereas non-CCM patients had lower RAP than baseline. Compared to patient without CCM, CCM patients revealed lower immediate (16.7 ± 4.4 vs. 18.9 ± 4.8, p = 0.022) and delayed 15.9 ± 3.7 vs. 17.7 ± 5.3, p = 0.044) portal vein pressures (PVP) and portal pressure gradients (PPG) (7.7 ± 3.4 vs. 9.2 ± 3.6, p = 0.032 and 10.1 ± 3.1 vs. 12.3 ± 4.9, p = 0.013). The 1-year mortality rates were 13.2% for CCM patients and 4.3% for non-CCM patients (log-rank test, p = 0.093), with MELD score, and preoperative RAP significantly associated with the mortality.

conclusionCirrhotic patients with CCM exhibit lower PVP and PPG immediately after TIPS and 2-4 days later, without significantly impacting one-year survival outcomes.

Indexed as

CardiomyopathiesHemodynamicsLiver CirrhosisPortasystemic Shunt, Transjugular IntrahepaticAgedEchocardiographyFemaleHumansHypertension, PortalMaleMiddle AgedPostoperative ComplicationsProspective StudiesCirrhosisCirrhotic cardiomyopathy (CCM)Portal hypertensionTransjugular intrahepatic portosystemic shunt (TIPS)

Identifiers

PMID38900326

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.