Evidence map›Paper›PMID 38900249›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2024

Effect of mGluR

Imane Frouni, Cynthia Kwan, Dominique Bédard, Adjia Hamadjida, Woojin Kang, Sébastien Belliveau, Stephen G Nuara, Jim C Gourdon, Philippe Huot

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Imane FrouniNeurodegenerative Disease Group, Montreal Neurological Institute-Hospital (The Neuro), 3801 University St, Montreal, Quebec, H3A 2B4, Canada.
Cynthia KwanNeurodegenerative Disease Group, Montreal Neurological Institute-Hospital (The Neuro), 3801 University St, Montreal, Quebec, H3A 2B4, Canada.
Dominique BédardNeurodegenerative Disease Group, Montreal Neurological Institute-Hospital (The Neuro), 3801 University St, Montreal, Quebec, H3A 2B4, Canada.
Adjia HamadjidaNeurodegenerative Disease Group, Montreal Neurological Institute-Hospital (The Neuro), 3801 University St, Montreal, Quebec, H3A 2B4, Canada.
Woojin KangNeurodegenerative Disease Group, Montreal Neurological Institute-Hospital (The Neuro), 3801 University St, Montreal, Quebec, H3A 2B4, Canada.
Sébastien BelliveauNeurodegenerative Disease Group, Montreal Neurological Institute-Hospital (The Neuro), 3801 University St, Montreal, Quebec, H3A 2B4, Canada.
Stephen G NuaraComparative Medicine & Animal Resource Centre, McGill University, Montreal, Quebec, Canada.
Jim C GourdonComparative Medicine & Animal Resource Centre, McGill University, Montreal, Quebec, Canada.
Philippe HuotNeurodegenerative Disease Group, Montreal Neurological Institute-Hospital (The Neuro), 3801 University St, Montreal, Quebec, H3A 2B4, Canada. philippe.huot@mcgill.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have previously discovered that the selective activation of metabotropic glutamate type 2 receptors (mGluR

Indexed as

Receptors, Metabotropic GlutamateAmino AcidsAnimalsAntiparkinson AgentsBridged Bicyclo CompoundsBridged Bicyclo Compounds, HeterocyclicCallithrixCyclohexanesExcitatory Amino Acid AgonistsFemaleHypokinesiaLevodopaMaleMotor ActivityMPTP PoisoningParkinsonian Disorders2-amino-3-((3,4-difluorophenyl)sulfanylmethyl)-4-hydroxy-bicyclo(3.1.0)hexane-2,6-dicarboxylic acid hydrochlorideAmino AcidsAntiparkinson AgentsBridged Bicyclo CompoundsBridged Bicyclo Compounds, HeterocyclicCyclohexaneseglumetadExcitatory Amino Acid AgonistsistradefyllineLevodopaLY 379268metabotropic glutamate receptor 2metabotropic glutamate receptor 3N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2-trifluoroethylsulfonyl)pyrid-3-ylmethylaminePurinesPyridinesReceptors, Metabotropic GlutamateSulfonamidesCBiPESLY-354,740LY-404,039LY-487,379MarmosetmGluR2mGluR2/3MPTPParkinsonismParkinson’s disease

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.