ArticleRadiology. Cardiothoracic imaging2024
Arrhythmic Mitral Valve Prolapse Phenotype: An Unsupervised Machine Learning Analysis Using a Multicenter Cardiac MRI Registry.
Abstract readMulticenter Study
In one paragraph
Article in Radiology. Cardiothoracic imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10citing papers in PubMed
–field-weighted citation impact
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Explainable machine learning and unsupervised anatomical phenotyping of mitral valve prolapse in patients with severe mitral regurgitation.BMC cardiovascular disorders · 2026Article
- Doming Volume in Mitral Valve Prolapse: Pathophysiology, Imaging Implications and Clinical Relevance.Journal of cardiovascular development and disease · 2026Review
- Mitral Annular Disjunction and Arrhythmic Risk: Case Series and State of the Art.Biomedicines · 2025Article
- Phenotyping of Mitral Valve Prolapse Without Severe Mitral Regurgitation Using Electrocardiographic and Echocardiographic Data.JACC. Clinical electrophysiology · 2025Article
- Reversed Remodeling Unveils Mitral Annular Disjunction.JACC. Case reports · 2025Article
- Review
- The Prevalence, Pathophysiological Role and Determinants of Mitral Annular Disjunction Among Patients with Mitral Valve Prolapse: A Systematic Review.Journal of clinical medicine · 2025Review
- Left ventricular hypertrophy and ventricular ectopy in mitral valve prolapse.International journal of cardiology · 2025Article
- Feasibility and Role of Cardiac Magnetic Resonance in Intensive and Acute Cardiovascular Care.Journal of clinical medicine · 2025Review
- Phenotypic Heterogeneity in Mitral Valve Prolapse: Insights from a Case Series.Journal of cardiovascular echographyArticle
Corrections and comments
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Authors and funding
42 authors.
Ralph Kwame Akyea *From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0003-4529-8237
Stefano Figliozzi *From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0003-2991-1548
Pedro M LopesFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-1536-7855
Klemens B BauerFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-7500-8846
Sara Moura-FerreiraFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0003-2909-9166
Lara TondiFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0001-7140-0341
Saima MushtaqFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).
Stefano CensiFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-9893-3508
Anna Giulia PavonFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-8001-1476
Ilaria BassiFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-4877-7789
Laura Galian-GayFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).
Arco J TeskeFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0001-5305-1619
Federico BiondiFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).
Domenico FilomenaFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-1515-506X
Vasileios StylianidisFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0009-0000-9047-9905
Camilla TorlascoFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0003-2382-6721
Denisa MuraruFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).
Pierre MonneyFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-3083-7333
Giuseppina QuattrocchiFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).
Viviana MaestriniFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-3225-8378
Luciano AgatiFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0003-3186-1797
Lorenzo MontiFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0001-6656-3568
Patrizia PedrottiFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0001-8920-1156
Bert VandenberkFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0001-8296-920X
Angelo SqueriFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0001-9115-5443
Massimo LombardiFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).
António M FerreiraFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-1623-7382
Juerg SchwitterFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-9966-6149
Giovanni Donato AquaroFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).
Gianluca PontoneFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-1339-6679
Amedeo ChiribiriFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0003-3394-4289
José F Rodríguez PalomaresFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-7229-9780
Ali YilmazFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).
Daniele AndreiniFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-5996-9209
Anca-Rezeda FlorianFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0001-5142-7686
Marco FranconeFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-7906-3420
Tim LeinerFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0003-1885-5499
João AbecasisFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-4741-8178
Luigi Paolo BadanoFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0002-0379-3283
Jan BogaertFrom the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).
Georgios Georgiopoulos *From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).ORCID 0000-0001-7661-5253
Pier-Giorgio Masci *From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose To use unsupervised machine learning to identify phenotypic clusters with increased risk of arrhythmic mitral valve prolapse (MVP). Materials and Methods This retrospective study included patients with MVP without hemodynamically significant mitral regurgitation or left ventricular (LV) dysfunction undergoing late gadolinium enhancement (LGE) cardiac MRI between October 2007 and June 2020 in 15 European tertiary centers. The study end point was a composite of sustained ventricular tachycardia, (aborted) sudden cardiac death, or unexplained syncope. Unsupervised data-driven hierarchical
Indexed as
Mitral Valve ProlapsePhenotypeUnsupervised Machine LearningAdultArrhythmias, CardiacFemaleHumansMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMaleMiddle AgedRegistriesRetrospective StudiesCardiacCardiac MRICluster AnalysisMitral Valve ProlapseMR ImagingSudden Cardiac DeathUnsupervised Machine LearningVentricular Arrhythmia
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.