Evidence map›Paper›PMID 38899880›Full record

ArticleInfection and immunity2024

The atypical antipsychotic aripiprazole alters the outcome of disseminated

Parker Reitler, Jessica Regan, Christian DeJarnette, Ashish Srivastava, Jen Carnahan, Katie M Tucker, Bernd Meibohm, Brian M Peters, Glen E Palmer

Abstract read
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Parker ReitlerIntegrated Program in Biomedical Sciences, University of Tennessee Health Science Center, Memphis, Tennessee, USA.ORCID 0009-0008-4216-7294
Jessica ReganPharmaceutical Sciences Program, College of Graduate Health Sciences, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Christian DeJarnetteDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Ashish SrivastavaDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Jen CarnahanDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Katie M TuckerDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Bernd MeibohmDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.ORCID 0000-0003-3923-3648
Brian M PetersDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.ORCID 0000-0002-0445-2077
Glen E PalmerDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.ORCID 0000-0003-4083-3130

Funding

Antifungal antagonism as a cause of treatment failure for invasive mycosesR01AI152067 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI PALMER, GLEN · 2021 to 2025
$3.1M
Candidalysin: a key mediator of Candida vaginitis immunopathologyR01AI134796 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI Brian M Peters · 2018 to 2026
$2.9M
Broad spectrum antifungals targeting fatty acid biosynthesisR33AI127607 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI PALMER, GLEN · 2019 to 2022
$1.5M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI134796HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI152067, R33AI127067NIAID NIH HHS R01 AI134796NIAID NIH HHS R01 AI152067NIAID NIH HHS R33 AI127607
6 · The paper itself

Abstract

Invasive fungal infections impose an enormous clinical, social, and economic burden on humankind. One of the most common species responsible for invasive fungal infections is

Indexed as

Antifungal AgentsAripiprazoleCandida albicansCandidiasisAnimalsAntipsychotic AgentsAzolesDisease Models, AnimalFemaleMiceVirulenceAntifungal AgentsAntipsychotic AgentsAripiprazoleAzolesantifungal antagonismCandida albicansdrug-fungus interactionfitnesshost-pathogen interactionTac1p

Identifiers

PMID38899880
PMCPMC11238555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.