Evidence map›Paper›PMID 38899186›Full record

ArticleKidney international reports2024

Best Practice of Peritoneal Dialysis-Associated Gram-Negative Peritonitis in Children: Insights From the International Pediatric Peritoneal Dialysis Network Registry.

Dagmara Borzych-Dużałka, Rebeca Same, Alicia Neu, Hui Kim Yap, Enrico Verrina, Sevcan A Bakkaloglu, Francisco Cano, Hiren Patel, Maria Szczepańska, Łukasz Obrycki and 12 more

Abstract read
In one paragraph

Article in Kidney international reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Acquired cystic kidney disease in children with kidney failure.Pediatric nephrology (Berlin, Germany) · 2025
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Dagmara Borzych-DużałkaDepartment for Pediatrics, Nephrology and Hypertension, Medical University of Gdańsk, Gdańsk, Poland.
Rebeca SameChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Alicia NeuJohns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Hui Kim YapDepartment of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Enrico VerrinaIRCCS Instituto Giannina Gaslini, Genoa, Italy.
Sevcan A BakkalogluGazi University Hospital, Ankara, Turkey.
Francisco CanoDivision of Pediatric Nephrology, Hospital Dr. Luis Calvo Mackenna, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Hiren PatelNationwide Children's Hospital, Columbus, Ohio, USA.
Maria SzczepańskaDepartment of Pediatrics, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland.
Łukasz ObryckiChildren's Memorial Health Institute, Warsaw, Poland.
Ana Paula SpizzirriDivision of Pediatric Nephrology, Hospital for Maria Ludovica, La Plata, Argentina.
Lisa SartzDepartment of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.
Karel VondrakUniversity Hospital Motol, Prague, Czech Republic.
Anabella ReboriSENIAD, Montevideo, Uruguay.
Gordana Milosevski-LomicChildren's University Hospital, Belgrade, Serbia.
Eugene Yu-Hin ChanPediatric Nephrology Centre, Hong Kong Children's Hospital, Kowloon Bay, Hong Kong SAR.
Biswanath BasuNRS Medical College and Hospital, Kolkata, India.
Andrea Lazcano PezoRoberto del Rio Hospital, Chile.
Ariane ZaloszycPediatric Nephrology, Pédiatrie 1, Centre Hospitalier Universitaire de Strasbourg, France.
Vimal ChadhaChildren's Mercy Kansas City, Kansas City, Missouri, USA.
Franz SchaeferUniversity Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany.
Bradley A WaradyChildren's Mercy Kansas City, Kansas City, Missouri, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Gram-negative peritonitis (GNP) is associated with significant morbidity in children receiving long-term peritoneal dialysis (PD) and current treatment recommendations are based on limited data. Methods: Analysis of 379 GNP episodes in 308 children (median age 6.9 years, interquartile range [IQR]: 3.0-13.6) from 45 centers in 28 countries reported to the International Pediatric Peritoneal Dialysis Network registry between 2011 and 2023. Results: Overall, 74% of episodes responded well to empiric therapy and full functional recovery (FFR) was achieved in 82% of cases. Conclusion: Detailed microbiological assessment, consisting of patient-specific and center-specific antimicrobial susceptibility data, should guide empiric treatment. Treatment "deescalation" with the use of monotherapy and narrow spectrum antibiotics according to susceptibility data is not associated with inferior outcomes and should be advocated in the context of emerging bacterial resistance.

Indexed as

childrenEnterobacteralesgram-negativePD-associated peritonitisPseudomonas

Identifiers

PMID38899186
PMCPMC11184244

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.