Evidence map›Paper›PMID 38899039›Full record

ArticleBioMed research international2024

Antimicrobial, Anti-inflammatory, and Wound Healing Properties of

Zohre Jafari, Hassan Bardania, Mehrzad Jafari Barmak, Saba Eslami, Yaser Mahmoudi-Mourderaz, Narges Roustaei, Mohammad Sharif Talebianpoor, Esmaeel Panahi Kokhdan, Seyed Sajjad Khoramrooz

Abstract read
In one paragraph

Article in BioMed research international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zohre JafariStudent Research Committee Yasuj University of Medical Sciences, Yasuj, Iran.ORCID https://orcid.org/0000-0001-9344-0061
Hassan BardaniaCellular and Molecular Research Canter Yasuj University of Medical Sciences, Yasuj, Iran.ORCID https://orcid.org/0000-0001-8799-173X
Mehrzad Jafari BarmakCellular and Molecular Research Canter Yasuj University of Medical Sciences, Yasuj, Iran.ORCID https://orcid.org/0000-0001-7240-6614
Saba EslamiShiraz University of Medical Sciences, Shiraz, Iran.ORCID https://orcid.org/0000-0002-4148-3470
Yaser Mahmoudi-MourderazStudent Research Committee Yasuj University of Medical Sciences, Yasuj, Iran.ORCID https://orcid.org/0000-0003-4256-048X
Narges RoustaeiDepartment of Epidemiology and Biostatistics School of Health and Nutrition Sciences Social Determinants of Health Research Center Yasuj University of Medical Sciences, Yasuj, Iran.ORCID https://orcid.org/0000-0002-5753-2142
Mohammad Sharif TalebianpoorMedicinal Plants Research Center Yasuj University of Medical Sciences, Yasuj, Iran.ORCID https://orcid.org/0000-0003-2956-1779
Esmaeel Panahi KokhdanMedicinal Plants Research Center Yasuj University of Medical Sciences, Yasuj, Iran.ORCID https://orcid.org/0000-0002-8470-8844
Seyed Sajjad KhoramroozMedicinal Plants Research Center Yasuj University of Medical Sciences, Yasuj, Iran.ORCID https://orcid.org/0000-0002-6215-1619

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Materials and Methods: In a research experiment, 48 male Wistar rats were anesthetized and second-degree burns were induced on their backs. The rats' wounds were then uniformly inoculated with MRSA. Various treatments were applied to the burn wounds daily, including Myrtus ointment, silver nanoparticles, silver nanoparticles-Myrtus ointment, silver sulfadiazine-Myrtus ointment, silver sulfadiazine 1%, mupirocin ointment, and a positive control. The study measured the antimicrobial effects, wound area, percentage of wound healing, antioxidant capacities, malondialdehyde, and nitric oxide concentrations in the serum of the rats. Data analysis was performed using GraphPad software, with one-way ANOVA and Tukey's tests used to determine the statistical significance of the results. Results: Rats treated with Myrtus ointment, silver nanoparticles-Myrtus ointment, and mupirocin had reduced bacterial growth compared to the positive control group, nanoparticle ointment, and silver sulfadiazine ( Conclusion: Based on the anti-inflammatory, antimicrobial, and wound healing properties of Myrtus, with further studies, an ointment of this plant may be used as a main or complementary treatment for burn wound infections caused by MRSA.

Indexed as

Anti-Inflammatory AgentsBurnsMethicillin-Resistant Staphylococcus aureusMyrtusOintmentsPlant ExtractsPlant LeavesRats, WistarWound HealingAnimalsAnti-Infective AgentsMaleMetal NanoparticlesRatsSilver SulfadiazineStaphylococcal InfectionsAnti-Infective AgentsAnti-Inflammatory AgentsOintmentsPlant ExtractsSilver Sulfadiazine

Identifiers

PMID38899039
PMCPMC11186692

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.