Evidence map›Paper›PMID 38898857›Full record

ArticleWorld journal of clinical cases2024

Dosimetric risk factors for radiation esophagitis in patients with breast cancer following regional nodal radiation.

Mei-Chen Ji, Zhi-Jia Li, Ke Li, Yun-Xiao Wang, Bo Yang, Lin-Lin Lv, Ying Su, Zhi-Wei Zhang, Zhong-Chao Huo, Qing Qi and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical cases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mei-Chen JiOncology Center, The Affiliated Hospital of Hebei University of En-gineering, Handan 056002, Hebei Province, China.
Zhi-Jia LiOncology Center, The Affiliated Hospital of Hebei University of En-gineering, Handan 056002, Hebei Province, China.
Ke LiOncology Center, The Affiliated Hospital of Hebei University of En-gineering, Handan 056002, Hebei Province, China.
Yun-Xiao WangOncology Center, The Affiliated Hospital of Hebei University of En-gineering, Handan 056002, Hebei Province, China.
Bo YangOncology Center, The Affiliated Hospital of Hebei University of En-gineering, Handan 056002, Hebei Province, China.
Lin-Lin LvOncology Center, The Affiliated Hospital of Hebei University of En-gineering, Handan 056002, Hebei Province, China.
Ying SuOncology Center, The Affiliated Hospital of Hebei University of En-gineering, Handan 056002, Hebei Province, China.
Zhi-Wei ZhangOncology Center, The Affiliated Hospital of Hebei University of En-gineering, Handan 056002, Hebei Province, China.
Zhong-Chao HuoOncology Center, The Affiliated Hospital of Hebei University of En-gineering, Handan 056002, Hebei Province, China.
Qing QiOncology Center, The Affiliated Hospital of Hebei University of En-gineering, Handan 056002, Hebei Province, China. qiqing365@163.com.
Yong-Chang LuGeneral Surgery Department, Handan First Hospital, Handan 056002, Hebei Province, China.
Zhi-Qiang CuiDepartment of Breast Surgery, The Affiliated Hospital of Hebei University of Engineering, Handan 056002, Hebei Province, China.
Yan-Bao LiuSchool of Clinical Medicine, Hebei University of Engineering, Handan 056002, Hebei Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadiation esophagitis (RE) is one of the most common clinical symptoms of regi-onal lymph node radiotherapy for breast cancer. However, there are fewer studies focusing on RE caused by hypofractionated radiotherapy (HFRT).

aimTo analyze the clinical and dosimetric factors that contribute to the development of RE in patients with breast cancer treated with HFRT of regional lymph nodes.

methodsBetween January and December 2022, we retrospectively analysed 64 patients with breast cancer who met our inclusion criteria underwent regional nodal intensity-modulated radiotherapy at a radiotherapy dose of 43.5 Gy/15F.

resultsOf the 64 patients in this study, 24 (37.5%) did not develop RE, 29 (45.3%) developed grade 1 RE (G1RE), 11 (17.2%) developed grade 2 RE (G2RE), and none developed grade 3 RE or higher. Our univariable logistic regression analysis found G2RE to be significantly correlated with the maximum dose, mean dose, relative volume 20-40, and absolute volume (AV) 20-40. Our stepwise linear regression analyses found AV30 and AV35 to be significantly associated with G2RE (

conclusionAV30 and AV35 were significantly associated with G2RE. The thresholds for AV30 and AV35 should be limited to 2.39 mL and 0.71 mL, respectively.

Indexed as

Breast cancerDosimetric parametersEsophagitisHypofractionated radiotherapyRadiation esophagitis

Identifiers

PMID38898857
PMCPMC11185373

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.