Evidence map›Paper›PMID 38898603›Full record

ArticleBiochemistry2024

An Unusual Ferryl Intermediate and Its Implications for the Mechanism of Oxacyclization by the Loline-Producing Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, LolO.

Juan Pan, Eliott S Wenger, Chi-Yun Lin, Bo Zhang, Debangsu Sil, Irene Schaperdoth, Setareh Saryazdi, Robert B Grossman, Carsten Krebs, J Martin Bollinger

Abstract read
In one paragraph

Article in Biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Juan PanDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0003-3307-958X
Eliott S WengerDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0001-6391-8036
Chi-Yun LinDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0001-6555-8767
Bo ZhangDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0003-0212-8879
Debangsu SilDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0002-0718-3925
Irene SchaperdothDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0001-5240-3475
Setareh SaryazdiDepartment of Chemistry, The University of Kentucky, Lexington, Kentucky 40506, United States.
Robert B GrossmanDepartment of Chemistry, The University of Kentucky, Lexington, Kentucky 40506, United States.ORCID 0000-0001-8866-3754
Carsten KrebsDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0002-3302-7053
J Martin BollingerDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0003-0751-8585

Funding

Mechanisms of Mononuclear non-Heme-Iron EnzymesR35GM127079 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI CARSTEN KREBS · 2018 to 2026
$3.8M
Mechanisms of oxacycle- and olefin-installing iron/2-(oxo)glutarate oxygenasesR01GM113106 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI BOLLINGER, JOSEPH M, KREBS, CARSTEN · 2015 to 2018
$1.8M
Mechanisms and Reprogramming of Iron/2-Oxoglutarate Desaturases and OxacyclasesR01GM118812 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI BOLLINGER, JOSEPH M, KREBS, CARSTEN · 2016 to 2019
$1.0M
NIGMS NIH HHS R01 GM113106NIGMS NIH HHS R01 GM118812NIGMS NIH HHS R35 GM127079
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

IronKetoglutaric AcidsBacterial ProteinsCyclizationHydroxylationOxygenasesBacterial ProteinsIronKetoglutaric AcidsOxygenases

Identifiers

PMID38898603
PMCPMC11219260

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.