Evidence map›Paper›PMID 38898483›Full record

ReviewLaboratory animal research2024

Non-classical animal models for studying adrenal diseases: advantages, limitations, and implications for research.

Alina Bilyalova, Airat Bilyalov, Nikita Filatov, Elena Shagimardanova, Andrey Kiyasov, Maria Vorontsova, Oleg Gusev

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Laboratory animal research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alina BilyalovaInstitute of fundamental medicine and biology, Kazan Federal University, Kazan, 420008, Russia.
Airat BilyalovInstitute of fundamental medicine and biology, Kazan Federal University, Kazan, 420008, Russia.
Nikita FilatovInstitute of fundamental medicine and biology, Kazan Federal University, Kazan, 420008, Russia.
Elena ShagimardanovaLoginov Moscow Clinical Scientific Center, Moscow, 111123, Russia.
Andrey KiyasovInstitute of fundamental medicine and biology, Kazan Federal University, Kazan, 420008, Russia.
Maria VorontsovaLomonosov Moscow State University, Moscow, 119991, Russia.
Oleg GusevLife Improvement by Future Technologies (LIFT) Center, Moscow, 121205, Russia. o.gusev.fo@juntendo.ac.jp.ORCID http://orcid.org/0000-0002-6203-9758

Funding

075-15-2021-1344 075-15-2021-1344
6 · The paper itself

Abstract

The study of adrenal disorders is a key component of scientific research, driven by the complex innervation, unique structure, and essential functions of the adrenal glands. This review explores the use of non-traditional animal models for studying congenital adrenal hyperplasia. It highlights the advantages, limitations, and relevance of these models, including domestic ferrets, dogs, guinea pigs, golden hamsters, pigs, and spiny mice. We provide a detailed analysis of the histological structure, steroidogenesis pathways, and genetic characteristics of these animal models. The morphological and functional similarities between the adrenal glands of spiny mice and humans highlight their potential as an important avenue for future research.

Indexed as

Adrenal glandAnimal modelsCAH, spiny mouse, golden hamsterSteroidogenesis

Identifiers

PMID38898483
PMCPMC11186145

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.