Evidence map›Paper›PMID 38898437›Full record

ArticleInternational journal for equity in health2024

Global, regional, and national health inequalities of Alzheimer's disease and Parkinson's disease in 204 countries, 1990-2019.

Zixiang Ji, Qi Chen, Jing Yang, Jiazhe Hou, Hengjing Wu, Lijuan Zhang

Abstract read
In one paragraph

Article in International journal for equity in health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Senotherapeutics for Brain Aging Management.Neurology international · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Intersection of HNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zixiang JiClinical Center for Intelligent Rehabilitation Research, Shanghai YangZhi Rehabilitation Hospital Tongji University School of Medicine, Tongji University, Shanghai, 201619, China.
Qi ChenSchool of Public Health, Nanjing Medical University, Nanjing, Jiangsu province, 211166, China.
Jing YangClinical Center for Intelligent Rehabilitation Research, Shanghai YangZhi Rehabilitation Hospital Tongji University School of Medicine, Tongji University, Shanghai, 201619, China.
Jiazhe HouClinical Center for Intelligent Rehabilitation Research, Shanghai YangZhi Rehabilitation Hospital Tongji University School of Medicine, Tongji University, Shanghai, 201619, China.
Hengjing WuClinical Center for Intelligent Rehabilitation Research, Shanghai YangZhi Rehabilitation Hospital Tongji University School of Medicine, Tongji University, Shanghai, 201619, China.
Lijuan ZhangClinical Center for Intelligent Rehabilitation Research, Shanghai YangZhi Rehabilitation Hospital Tongji University School of Medicine, Tongji University, Shanghai, 201619, China. zhangxiaoyi@tongji.edu.cn.

Funding

the National Natural Science Foundation of China 81872720
6 · The paper itself

Abstract

backgroundAlzheimer's disease and related dementias (ADRD) and Parkinson's disease (PD), pose growing global health challenges. Socio-demographic and economic development acts paradoxically, complicating the process that determines how governments worldwide designate policies and allocate resources for healthcare.

methodsWe extracted data on ADRD and PD in 204 countries from the Global Burden of Disease 2019 database. Health disparities were estimated using the slope index of inequality (SII), and concentration index (CIX) based on the socio-demographic index. Estimated annual percentage changes (EAPCs) were employed to evaluate temporal trends.

resultsGlobally, the SII increased from 255.4 [95% confidence interval (CI), 215.2 to 295.5)] in 1990 to 559.3 (95% CI, 497.2 to 621.3) in 2019 for ADRD, and grew from 66.0 (95% CI, 54.9 to 77.2) in 1990 to 132.5 (95% CI, 118.1 to 147.0) in 2019 for PD; CIX rose from 33.7 (95% CI, 25.8 to 41.6) in 1990 to 36.9 (95% CI, 27.8 to 46.1) in 2019 for ADRD, and expanded from 22.2 (95% CI, 21.3 to 23.0) in 1990 to 29.0 (95% CI, 27.8 to 30.3) in 2019 for PD. Age-standardized disability-adjusted life years displayed considerable upward trends for ADRD [EAPC = 0.43 (95% CI, 0.27 to 0.59)] and PD [0.34 (95% CI, 0.29 to 0.38)].

conclusionsGlobally, the burden of ADRD and PD continues to increase with growing health disparities. Variations in health inequalities and the impact of socioeconomic development on disease trends underscored the need for targeted policies and strategies, with heightened awareness, preventive measures, and active management of risk factors.

Indexed as

Alzheimer DiseaseGlobal HealthParkinson DiseaseAgedFemaleGlobal Burden of DiseaseHealth InequitiesHealth Status DisparitiesHumansMaleMiddle AgedSocioeconomic Factors“Alzheimer Disease/epidemiology“[Mesh]“Disability-Adjusted Life Years /trends“[Mesh]“Global Burden of Disease/trends“[Mesh]“Health Inequities“[Mesh]“Incidence/trends“[Mesh]“Parkinson Disease/epidemiology“[Mesh]“Prevalence/trends“[Mesh]

Identifiers

PMID38898437
PMCPMC11188225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.