ArticleNature2024
Computational design of soluble and functional membrane protein analogues.
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Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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72citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
72 citing papers in PubMed.
- Graph-based representations in modern protein science.The Biochemical journal · 2026Review
- Unraveling the Glycosylation Machinery ofInternational journal of molecular sciences · 2026Article
- Sequence and structural determinants of efficacious de novo chimaeric antigen receptors.Nature biomedical engineering · 2026Article
- Plant immune receptors built in silico and evolved in vivo.Nature plants · 2026Article
- Soluble protein analog selection engine (SPASE): An automated AI-powered server to improve protein engineering workflows.Protein science : a publication of the Protein Society · 2026Article
- New paradigm of q-CAR drug development targeting disease-specific protein conformations.npj drug discovery · 2026Review
- Artificial intelligence in drug discovery - what it is, where we stand and the path forward.Nature reviews. Drug discovery · 2026Review
- Structure-forward targeting of claudins with synthetic binders.FEBS letters · 2026Review
- Artificial intelligence in biologic drug discovery: A review of methodological evolution and therapeutic applications.Acta pharmaceutica Sinica. B · 2026Review
- Overestimating zero-shot fitness prediction: Broad benchmarks mask local failures and practical limitations.bioRxiv : the preprint server for biology · 2026Article
- Tools For Building Artificial Biological Nanostructures.ACS nano · 2026Review
- Computer-aided structural modeling and drug discovery for G-protein-coupled receptors in the age of artificial intelligence.Current opinion in structural biology · 2026Review
- Limitations of the refolding pipeline for de novo protein design.Protein science : a publication of the Protein Society · 2026Article
- Article
- Stabilizing Plasmodium falciparum proteins for small molecule drug discovery.Protein science : a publication of the Protein Society · 2026Article
- AI-guided redesign of laboratory-evolved reverse transcriptases enhances prime editing.Nature biotechnology · 2026Article
- Reverse-engineering amyloid strains with generative protein design.bioRxiv : the preprint server for biology · 2026Article
- Activation dynamics of a water-soluble human mu-opioid receptor.The Journal of biological chemistry · 2026Article
- ProteinMCP: An agentic AI framework for autonomous protein engineering.Protein science : a publication of the Protein Society · 2026Article
- Review
12 more citing papers are in PubMed but not listed here.
Corrections and comments
- Update of
Authors and funding
16 authors.
Casper A Goverde *Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland.ORCID 0009-0004-7409-4705
Martin Pacesa *Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland.ORCID 0000-0003-1560-5769
Nicolas Goldbach *Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland.ORCID 0000-0001-5401-3892
Lars J DornfeldLaboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland.ORCID 0009-0009-0885-8443
Petra E M BalbiLaboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Sandrine GeorgeonLaboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Stéphane RossetLaboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Srajan KapoorDepartment of Structural Biology, University at Buffalo, Buffalo, NY, USA.
Jagrity ChoudhuryDepartment of Structural Biology, University at Buffalo, Buffalo, NY, USA.
Justas DauparasDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Christian SchellhaasLaboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland.ORCID 0000-0001-7367-1620
Simon KozlovDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
David BakerDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID 0000-0001-7896-6217
Sergey OvchinnikovDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID 0000-0003-2774-2744
Alex J VecchioDepartment of Structural Biology, University at Buffalo, Buffalo, NY, USA.ORCID 0000-0002-4222-7874
Bruno E CorreiaLaboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland. bruno.correia@epfl.ch.ORCID 0000-0002-7377-8636
Funding
Structure and Assembly of Membrane Proteins at Tight JunctionsR35GM138368 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI Alex J. Vecchio · 2020 to 2026
$3.1MExploring the unknown protein universe using evolutionary informationDP5OD026389 · OD · HARVARD UNIVERSITY · PI OVCHINNIKOV, SERGEY L. · 2018 to 2022
$2.0MNIGMS NIH HHS R35 GM138368NIH HHS DP5 OD026389
Abstract
De novo design of complex protein folds using solely computational means remains a substantial challenge
Indexed as
Computer-Aided DesignDeep LearningMembrane ProteinsProtein FoldingSolubilityAmino Acid MotifsHumansModels, MolecularProof of Concept StudyProtein StabilityProteomeReceptors, G-Protein-CoupledMembrane ProteinsProteomeReceptors, G-Protein-Coupled
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.