Evidence map›Paper›PMID 38898276›Full record

ArticleNature2024

An alternative broad-specificity pathway for glycan breakdown in bacteria.

Seyed Amirhossein Nasseri, Aleksander C Lazarski, Imke L Lemmer, Chloe Y Zhang, Eva Brencher, Hong-Ming Chen, Lyann Sim, Deepesh Panwar, Leo Betschart, Liam J Worrall and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Enzymatic 1,4-addition of 2-hydroxy-3-keto-glucal for β-selective aryl-Chemical communications (Cambridge, England) · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Activity-Based Tracking of Glycan Turnover in Microbiomes.Journal of the American Chemical Society · 2025
    Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Seyed Amirhossein NasseriDepartment of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-8380-7701
Aleksander C LazarskiDepartment of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-1364-2371
Imke L LemmerDepartment of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada.
Chloe Y ZhangMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0009-0005-9261-9744
Eva BrencherMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0009-0009-7537-5820
Hong-Ming ChenDepartment of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada.
Lyann SimMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.
Deepesh PanwarMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.
Leo BetschartDepartment of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-2609-5197
Liam J WorrallDepartment of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada.
Harry BrumerDepartment of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-0101-862X
Natalie C J StrynadkaDepartment of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-4058-9425
Stephen G WithersDepartment of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada. withers@chem.ubc.ca.ORCID 0000-0002-6722-5701

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vast majority of glycosidases characterized to date follow one of the variations of the 'Koshland' mechanisms

Indexed as

BacteriaGastrointestinal MicrobiomeGlycoside HydrolasesPolysaccharidesAcarboseBiocatalysisGlucosinolatesHumansHydrolysisMaleMetagenomeOxidation-ReductionPlantsSeawaterSoil MicrobiologySubstrate SpecificityAcarboseGlucosinolatesGlycoside HydrolasesPolysaccharides

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.