ArticleJournal of perinatology : official journal of the California Perinatal Association2024
Prenatal ultrasound markers for prediction of complex gastroschisis-single-center retrospective cohort study.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07030309 (MEGA STUDY - Multicenter Evaluation of Gastroschisis Anomaly Study), which is not on this map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
MEGA STUDY - Multicenter Evaluation of Gastroschisis Anomaly Study
Who cites it
4 citing papers in PubMed.
- Prenatal Diagnosis and Perinatal Management Considerations in Congenital Abdominal Wall Defects: A Case Series and Narrative Review.Journal of personalized medicine · 2026Article
- Fetal Superior Mesenteric Artery Peak Systolic Velocity as a Marker of Prenatal Bowel Inflammation in Gastroschisis: A Case-Control Study.Birth defects research · 2026Article
- Beyond the current limits: a novel approach to differentiate small and large intestine in gastroschisis through prenatal imaging.BMC pregnancy and childbirth · 2026Article
- Copy number variants in fetuses with isolated and non-isolated increased nuchal translucency detected by chromosomal microarray analysis.Frontiers in genetics · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate prenatal ultrasound markers for distinguishing simple gastroschisis (sGS) from complex gastroschisis (cGS) and identifying fetuses at risk of complications. STUDY
designA retrospective cohort study analyzed 61 fetuses with isolated gastroschisis at a tertiary center from 2011 to 2021, utilizing serial ultrasounds from 14 to 35 weeks' gestation. A general linear model, quantile regression, and logistic regression assessed ultrasound markers, fetal weeks, and gastroschisis risk, yielding predictive models.
resultsIABL dilatation showed the highest PPV but low NPV. Non-free floating bowel loops (NFFBL) indicated the best PPV to NPV ratio. Combinations of markers yielded the highest predictive value for cGS. EABL collapsed and non-free floating bowel loops were significant, consistent risk factors.
conclusionsPrenatal ultrasounds can predict cGS risk, particularly using IABL dilatation and NFFBL as markers. Accurate assessment requires considering gestational age, qualitative symptoms, emphasizing experienced perinatologists' role and monitoring, particularly after 30 weeks of gestation.
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Registered trials
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