Evidence map›Paper›PMID 38897635›Full record

ArticleArchives of disease in childhood. Fetal and neonatal edition2024

UK neonatal stoma practice: a population study.

Graciaa Singhal, Rema Ramakrishnan, Raph Goldacre, Cheryl Battersby, Nigel J Hall, Chris Gale, Marian Knight, Nick Lansdale

Abstract read
In one paragraph

Article in Archives of disease in childhood. Fetal and neonatal edition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Graciaa SinghalNeonatal Medicine, School of Public Health, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-6729-5622
Rema RamakrishnanNational Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-6784-8319
Raph GoldacreUnit of Health-Care Epidemiology, Department of Public Health, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-7393-1880
Cheryl BattersbyNeonatal Medicine, School of Public Health, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-2898-553X
Nigel J HallUniversity Surgery Unit, Faculty of Medicine, University of Southampton, Southampton, UK.ORCID http://orcid.org/0000-0001-8570-9374
Chris GaleNeonatal Medicine, School of Public Health, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-0707-876X
Marian KnightNational Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-1984-4575
Nick LansdaleDepartment of Paediatric and Neonatal Surgery, Royal Manchester Children's Hospital Department of Paediatric and Neonatal Surgery, Manchester, UK Nick.Lansdale2@mft.nhs.uk.ORCID http://orcid.org/0000-0002-0054-9250

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe optimal time for neonatal stoma closure is unclear and there have been calls for a trial to compare early and late surgery. The feasibility of such a trial will depend on the population of eligible infants and acceptability to families and health professionals. In this study, we aimed to determine current UK practice and characteristics of those undergoing stoma surgery.

designA retrospective cohort study of neonates who had undergone stoma surgery (excluding anorectal malformations and Hirschsprung's disease) using three national databases: the National Neonatal Research Database (NNRD, 2012-2019), British Association of Paediatric Surgeons Congenital Anomalies Surveillance System (BAPS-CASS, 2013-2014) and Hospital Episode Statistics-Admitted Patient Care (HES-APC, 2011-2018).

results1830 eligible neonates were identified from NNRD, 163 from BAPS-CASS, 2477 from HES-APC. Median (IQR) duration of stoma in days was 57 (36-80) in NNRD, 63 (41-130) in BAPS-CASS and 78 (55-122) for neonates identified from HES-APC. At the time of closure, there were low rates of invasive ventilation (13%), inotrope use (5%) and recent steroids use (4%). Infants who underwent earlier closure (<9 weeks) were less preterm (median 28 weeks vs 25 weeks), have higher birth weight (median 986 g vs 764 g) and more likely to have stoma complications (29% vs 5%).

conclusionThere are sufficient UK neonates undergoing stoma formation for a trial. Stoma closure is performed at around 2 months, with clinical stability, gestation, weight and stoma complications appearing to influence timing. The variation in practice we document indicates there is opportunity to optimise practice through a trial.

Indexed as

Surgical StomasColostomyFemaleHumansInfant, NewbornMaleRetrospective StudiesUnited KingdomGastroenterologyIntensive Care Units, NeonatalNeonatology

Identifiers

PMID38897635
PMCPMC11671890

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.