Evidence map›Paper›PMID 38897235›Full record

ReviewNeuroscience research2025

Large-scale foundation models and generative AI for BigData neuroscience.

Ran Wang, Zhe Sage Chen

Abstract readReview
In one paragraph

Review in Neuroscience research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Why the simplest explanation isn't always the best.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ran WangDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY 10016, USA.
Zhe Sage ChenDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY 10016, USA; Department of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY 10016, USA; Department of Biomedical Engineering, New York University Tandon School of Engineering, Brooklyn, NY 11201, USA. Electronic address: zhe.chen@nyulangone.org.

Funding

Thalamocortical cognitive networks in the healthy human brainP50MH132642 · NIMH · PRINCETON UNIVERSITY · PI SABINE KASTNER · 2023 to 2026
$15.7M
Machine learning approaches for improving EEG data utility in SUDEP researchR01NS123928 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DEVINSKY, ORRIN, FRIEDMAN, DANIEL · 2021 to 2025
$3.1M
Cortical information integration as a model for pain perception and behaviorRF1NS121776 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHEN, ZHE SAGE, WANG, JING · 2021 to 2021
$2.0M
CRNS: An Integrative Study of Hippocampal-Neocortical Memory Coding during Sleep R01MH118928 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHEN, ZHE SAGE, WILSON, MATTHEW A · 2018 to 2022
$1.8M
CRCN: Dissecting Neural Circuits for Acute PainR01NS100065 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHEN, ZHE SAGE, WANG, JING · 2016 to 2019
$1.5M
CRCNS: Dissection and control of cognitive thalamocortical dynamicsR01MH139352 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Zhe Sage Chen, Michael M Halassa · 2024 to 2026
$1.4M
Predictive Biosignature for Endoscopic Therapy for Chronic Pancreatitis PainUG3NS135170 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHEN, ZHE SAGE, DOAN, LISA · 2023 to 2023
$1.2M
Cortical Information Integration as a Model for Pain Perception and BehaviorR01NS121776 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHEN, ZHE SAGE, WANG, JING · 2024 to 2025
$1.2M
Dissection of spatiotemporal activity from large-scale, multi-modal, multi-resolution hippocampal-neocortical recordings.RF1DA056394 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BUZSAKI, GYORGY, CHEN, ZHE SAGE · 2022 to 2022
$1.1M
NIDA NIH HHS RF1 DA056394NIMH NIH HHS P50 MH132642NIMH NIH HHS R01 MH118928NIMH NIH HHS R01 MH139352NINDS NIH HHS R01 NS100065NINDS NIH HHS R01 NS121776NINDS NIH HHS R01 NS123928NINDS NIH HHS RF1 NS121776NINDS NIH HHS UG3 NS135170
6 · The paper itself

Abstract

Recent advances in machine learning have led to revolutionary breakthroughs in computer games, image and natural language understanding, and scientific discovery. Foundation models and large-scale language models (LLMs) have recently achieved human-like intelligence thanks to BigData. With the help of self-supervised learning (SSL) and transfer learning, these models may potentially reshape the landscapes of neuroscience research and make a significant impact on the future. Here we present a mini-review on recent advances in foundation models and generative AI models as well as their applications in neuroscience, including natural language and speech, semantic memory, brain-machine interfaces (BMIs), and data augmentation. We argue that this paradigm-shift framework will open new avenues for many neuroscience research directions and discuss the accompanying challenges and opportunities.

Indexed as

Artificial IntelligenceMachine LearningNeurosciencesBrain-Computer InterfacesHumansBigDataBrain-machine interfaceEmbeddingFoundation modelGenerative AIRepresentation learningSelf-supervised learningTransfer learningTransformer

Identifiers

PMID38897235
PMCPMC11649861

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.