Evidence map›Paper›PMID 38896467›Full record

ArticleMicrobial genomics2024

Expansion of pneumococcal serotype 23F and 14 lineages with genotypic changes in capsule polysaccharide locus and virulence gene profiles post introduction of pneumococcal conjugate vaccine in Blantyre, Malawi.

Rory Cave, Akuzike Kalizang'oma, Chrispin Chaguza, Thandie S Mwalukomo, Arox Kamng'ona, Comfort Brown, Jacquline Msefula, Farouck Bonomali, Roseline Nyirenda, Todd D Swarthout and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Genomic analysis ofMicrobial genomics · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Clinical microbiology reviews · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rory CaveMucosal Pathogens Research Group, Research Department of Infection, Division of Infection & Immunity, University College London, London, UK.
Akuzike Kalizang'omaMucosal Pathogens Research Group, Research Department of Infection, Division of Infection & Immunity, University College London, London, UK.
Chrispin ChaguzaParasites and Microbes, Wellcome Sanger Institute, Cambridge, UK.
Thandie S MwalukomoKamuzu University of Health Sciences, Blantyre, Malawi.
Arox Kamng'onaKamuzu University of Health Sciences, Blantyre, Malawi.
Comfort BrownMalawi Liverpool Wellcome Programme, Blantyre, Malawi.
Jacquline MsefulaKamuzu University of Health Sciences, Blantyre, Malawi.
Farouck BonomaliMalawi Liverpool Wellcome Programme, Blantyre, Malawi.
Roseline NyirendaMalawi Liverpool Wellcome Programme, Blantyre, Malawi.
Todd D SwarthoutMucosal Pathogens Research Group, Research Department of Infection, Division of Infection & Immunity, University College London, London, UK.
Brenda Kwambana-AdamsMucosal Pathogens Research Group, Research Department of Infection, Division of Infection & Immunity, University College London, London, UK.
Neil FrenchClinical Infection, Microbiology and Immunology, Institute of Infection Veterinary & Ecological Science, University of Liverpool, Liverpool, UK.
Robert S HeydermanMucosal Pathogens Research Group, Research Department of Infection, Division of Infection & Immunity, University College London, London, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Since the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) in Malawi in 2011, there has been persistent carriage of vaccine serotype (VT)

Indexed as

Bacterial CapsulesPneumococcal InfectionsPneumococcal VaccinesSerogroupStreptococcus pneumoniaeBacterial ProteinsChild, PreschoolGenotypeHumansInfantMalawiMalePolymorphism, Single NucleotidePolysaccharides, BacterialVaccines, ConjugateVirulence13-valent pneumococcal vaccineBacterial ProteinsPneumococcal VaccinesPolysaccharides, BacterialVaccines, ConjugateVirulence FactorsAfricaantimicrobial resistanceCapsule polysaccharide locusPCV13Streptococcus pneumoniaevaccine escape

Identifiers

PMID38896467
PMCPMC11261835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.