Evidence map›Paper›PMID 38896299›Full record

ArticleMarine biotechnology (New York, N.Y.)2024

HcN57, A Novel Unusual Acidic Silk-Like Matrix Protein from Hyriopsis cumingii, Participates in Framework Construction and Nacre Nucleation During Nacreous Layer Formation.

Can Jin, Fangmengjie Wei, Jiayi Zhang, Xiaoyang Tan, Taixia Fan, Wen Luo, Jiale Li

Abstract read
PubMed Publisher
In one paragraph

Article in Marine biotechnology (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Can JinSchool of Life and Environmental Sciences, Shaoxing University, Shaoxing, China.
Fangmengjie WeiSchool of Life and Environmental Sciences, Shaoxing University, Shaoxing, China.
Jiayi ZhangSchool of Life and Environmental Sciences, Shaoxing University, Shaoxing, China.
Xiaoyang TanSchool of Life and Environmental Sciences, Shaoxing University, Shaoxing, China.
Taixia FanSchool of Life and Environmental Sciences, Shaoxing University, Shaoxing, China.
Wen LuoSchool of Life and Environmental Sciences, Shaoxing University, Shaoxing, China. luowen@usx.edu.cn.
Jiale LiKey Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, 201306, China. jlli2009@126.com.

Funding

The National Natural Science Foundation of China 32202921
6 · The paper itself

Abstract

In the classic molecular model of nacreous layer formation, unusual acidic matrix proteins rich in aspartic acid (Asp) residues are essential for nacre nucleation due to their great affinity for binding calcium. However, the acidic matrix proteins discovered in the nacreous layer so far have been weakly acidic with a high proportion of glutamate. In the present study, several silk-like matrix proteins, including the novel matrix protein HcN57, were identified in the ethylenediaminetetraacetic acid-soluble extracts of the nacreous layer of Hyriopsis cumingii. HcN57 is a highly repetitive protein that consists of a high proportion of alanine (Ala, 34.4%), glycine (Gly, 22.5%), and serine (Ser, 11.4%). It forms poly Ala blocks, Gly

Indexed as

NacreAmino Acid SequenceAnimalsSilkSpidersNacreSilkHyriopsis cumingiiMatrix proteinNacreous layerNucleationSilkUnusual acidic

Identifiers

PMID38896299

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.