Evidence map›Paper›PMID 38896275›Full record

ArticleArchives of gynecology and obstetrics2024

The impact of fetal sex on pregnancy and neonatal outcomes in twin gestation.

O Eliner, H Schreiber, G Cohen, T Biron-Shental, M Kovo

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Article in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

O ElinerDepartment of Obstetrics and Gynecology, Meir Medical Center, Israel affiliate to Tel Aviv University, Kfar Saba, Israel. or.eliner@gmail.com.ORCID 0000-0002-6461-3557
H SchreiberDepartment of Obstetrics and Gynecology, Meir Medical Center, Israel affiliate to Tel Aviv University, Kfar Saba, Israel.
G CohenDepartment of Obstetrics and Gynecology, Meir Medical Center, Israel affiliate to Tel Aviv University, Kfar Saba, Israel.
T Biron-ShentalDepartment of Obstetrics and Gynecology, Meir Medical Center, Israel affiliate to Tel Aviv University, Kfar Saba, Israel.
M KovoDepartment of Obstetrics and Gynecology, Meir Medical Center, Israel affiliate to Tel Aviv University, Kfar Saba, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFetal sex is independently associated with pregnancy complications and impacts neonatal outcomes. Evidence suggests that females have an advantage over males, with a better outcome in the perinatal period. In addition, fetal outcome in twin gestations is also related to the intrauterine position of the fetus, such as the first, the presenting or second twin. It has been demonstrated that the neonatal outcome of the second fetus is worse than that of the first fetus. This study aimed to examine the influence of fetal sex on obstetric outcomes in twin pregnancies based on the location of the fetus in the uterus.

methodsRetrospective study. Maternal and obstetric outcomes were compared among three groups: male‒male, female‒female, and male‒female groups. Comparisons of neonatal outcomes were performed among the four groups: male A-male B, male A-female B, female A-male B, and female A-female B.

resultsA total of 1073 twin gestations were included, comprising 288 male‒male, 288 female‒female, and 497 male‒female gestations. A greater percentage of neonates admitted to the NICU was observed for male fetuses than for female fetuses. Adverse composite neonatal outcome was more common in the male‒male group than in the female‒male group and in the female‒female group.

conclusionTwin gestation with a first twin male tends to have worse neonatal outcomes than does twin gestation with a first twin female. The presence of a male co-twin increases the risk of adverse outcomes.

Indexed as

Pregnancy OutcomePregnancy, TwinAdultFemaleHumansInfant, NewbornMalePregnancyRetrospective StudiesSex FactorsFetal sexIntrauterine positionNeonatal outcomeTwin pregnancy

Identifiers

PMID38896275

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.