Evidence map›Paper›PMID 38896178›Full record

ReviewHead and neck pathology2024

Uremic Stomatitis: A Latin American Case Series and Literature Review.

José Alcides Almeida de Arruda, João Luiz Gomes Carneiro Monteiro, Maria Eduarda Zeraik Barreto, Mariana Villarroel-Dorrego, Gerardo Gilligan, René Panico, Thayanne Brasil Barbosa Calcia, Shimelly Monteiro de Castro Lara, Alice Maria de Oliveira Silva, Saray Aranda-Romo and 4 more

Abstract readReviewCase Reports
In one paragraph

Review in Head and neck pathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

José Alcides Almeida de ArrudaDepartment of Oral Diagnosis and Pathology, School of Dentistry, Universidade Federal do Rio de Janeiro, R. Rodolpho Paulo Rocco, n. 325, 1st floor, Cidade Universitária, Rio de Janeiro, RJ, Brazil. alcides_almeida@hotmail.com.
João Luiz Gomes Carneiro MonteiroDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Maria Eduarda Zeraik BarretoDepartment of Oral Diagnosis and Pathology, School of Dentistry, Universidade Federal do Rio de Janeiro, R. Rodolpho Paulo Rocco, n. 325, 1st floor, Cidade Universitária, Rio de Janeiro, RJ, Brazil.
Mariana Villarroel-DorregoSchool of Dentistry, Universidad Central de Venezuela, Caracas, Venezuela.
Gerardo GilliganDepartment of Oral Medicine, Facultad de Odontología, Universidad Nacional de Córdoba, Córdoba, Argentina.
René PanicoDepartment of Oral Medicine, Facultad de Odontología, Universidad Nacional de Córdoba, Córdoba, Argentina.
Thayanne Brasil Barbosa CalciaPetrópolis Medical School, Centro Universitário Arthur Sá Earp Neto, Petrópolis, Brazil.
Shimelly Monteiro de Castro LaraHospital das Clínicas de Teresópolis Costantino Ottaviano, Teresópolis, Brazil.
Alice Maria de Oliveira SilvaHospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
Saray Aranda-RomoDiagnostic Clinic, School of Dentistry, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico.
Francisco Javier Tejeda-NavaDiagnostic Clinic, School of Dentistry, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico.
Mônica Simões IsraelDepartment of Diagnosis and Therapeutics, School of Dentistry, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Tarcília Aparecida SilvaDepartment of Oral Surgery, Pathology and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Bruno Augusto Benevenuto de AndradeDepartment of Oral Diagnosis and Pathology, School of Dentistry, Universidade Federal do Rio de Janeiro, R. Rodolpho Paulo Rocco, n. 325, 1st floor, Cidade Universitária, Rio de Janeiro, RJ, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 302627/2022-7Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/201.289/2022; E-26/200.331/2024
6 · The paper itself

Abstract

backgroundUremic stomatitis is often unfamiliar to healthcare professionals. This study presents five cases of uremic stomatitis, providing a comprehensive analysis of their demographic distribution, clinicopathological features, and management strategies based on existing literature.

methodsData were collected from centers across Brazil, Argentina, Venezuela, and Mexico. Electronic searches were conducted in five databases supplemented by manual scrutiny and gray literature.

resultsThe series consisted of three men and two women with a mean age of 40.2 years. Lesions mostly appeared as white plaques, particularly on the tongue (100%). The median blood urea level was 129 mg/dL. Histopathological analysis revealed epithelial changes, including acanthosis and parakeratosis, with ballooned keratinocytes in the suprabasal region. Oral lesions resolved subsequent to hemodialysis in three cases (75%). Thirty-seven studies comprising 52 cases of uremic stomatitis have been described hitherto. Most patients were male (65.4%) with a mean age of 43.6 years. Clinically, grayish-white plaques (37.3%) and ulcers/ulcerations (28.9%) were common, particularly on the tongue (30.9%). Hemodialysis was performed on 27 individuals. The resolution rate of oral lesions was 53.3%.

conclusionEarlier recognition of uremic stomatitis, possibly associated with long-term uremia, holds the potential to improve outcomes for patients with undiagnosed chronic kidney disease.

Indexed as

StomatitisUremiaAdultFemaleHumansLatin AmericaMaleMiddle AgedRenal DialysisChronic Renal FailureKidneyOral ManifestationsStomatitisUrea

Identifiers

PMID38896178
PMCPMC11187249

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.