Evidence map›Paper›PMID 38895383›Full record

ArticlebioRxiv : the preprint server for biology2024

Protein Editing using a Concerted Transposition Reaction.

Yi Hua, Nicholas E S Tay, Xuanjia Ye, Jeremy A Owen, Hengyuan Liu, Robert E Thompson, Tom W Muir

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yi HuaDepartment of Chemistry, Princeton University, Princeton, NJ, USA.
Nicholas E S TayDepartment of Chemistry, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-4063-8880
Xuanjia YeDepartment of Chemistry, Princeton University, Princeton, NJ, USA.
Jeremy A OwenDepartment of Chemistry, Princeton University, Princeton, NJ, USA.
Hengyuan LiuDepartment of Chemistry, Princeton University, Princeton, NJ, USA.
Robert E ThompsonDepartment of Chemistry, Princeton University, Princeton, NJ, USA.
Tom W MuirDepartment of Chemistry, Princeton University, Princeton, NJ, USA.

Funding

Structure, Function and Applications of InteinsR01GM086868 · NIGMS · ROCKEFELLER UNIVERSITY · PI MUIR, TOM · 2008 to 2025
$4.4M
New Proximity Labeling Tools for Studying 3D Chromatin Structure and FunctionF32GM149123 · NIGMS · PRINCETON UNIVERSITY · PI TAY, NICHOLAS ENG SOON · 2023 to 2025
$233k
NIGMS NIH HHS F32 GM149123NIGMS NIH HHS R01 GM086868
6 · The paper itself

Abstract

Protein engineering through the chemical or enzymatic ligation of polypeptide fragments has proven enormously powerful for studying countless biochemical processes

Identifiers

PMID38895383
PMCPMC11185735

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.