In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
24 authors.
Stephen D CarterMRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK.ORCID 0000-0002-4237-4276 Eric K F DonahueDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.ORCID 0000-0002-7547-3959 Matias A PreiseggerDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.
Leanna EisenmanDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.
Cedric Bouchet-MarquisMaterials and Structural Analysis, Thermo Fisher Scientific, Hillsboro, OR, USA.
Ken WuMaterials and Structural Analysis, Thermo Fisher Scientific, Hillsboro, OR, USA.
Amber N FrantzDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Stephanie PuigDepartment of Psychiatry, University of Massachusetts Chan Medical School, Worcester, MA, USA.ORCID 0000-0001-7200-1094 Lief E FennoDepartments of Psychiatry and Neuroscience, University of Texas Austin Dell Medical School, Austin, TX, USA.ORCID 0000-0002-5237-6179 Kristopher BurkewitzDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.
Funding
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3MMechanism of MRNA Localization and Localized Translation in NeuronsR01NS083085 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Sulagna Das, Robert H Singer · 2013 to 2026
$9.0MEnhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5MMedical Scientist Training ProgramT32GM152284 · NIGMS · VANDERBILT UNIVERSITY · PI Christopher S. Williams · 2024 to 2026
$4.8MMechanisms of Pain Associated with Trigeminal Nerve InjuryR01NS122784 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GOLD, MICHAEL S, SEKULA, RAYMOND F · 2021 to 2025
$2.8MImaging large macromolecular complexes inside cells with electron cryotomographyR35GM122588 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI JENSEN, GRANT J · 2017 to 2020
$1.9MRequest for a ThermoFisher Helios 5UC DualBeamS10MH133575 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FREYBERG, ZACHARY, GLAUSIER, JILL RENEE' · 2023 to 2023
$600kTemporal dynamics of Arc (Arg3.1) transcriptional regulationR21MH122961 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI DAS, SULAGNA · 2021 to 2022
$462kElucidating the role of ER remodeling in aging of C. elegansF31AG076290 · NIA · VANDERBILT UNIVERSITY · PI DONAHUE, ERIC KF · 2022 to 2024
$118kNIA NIH HHS F31 AG076290NIGMS NIH HHS R35 GM122588NIGMS NIH HHS T32 GM007347NIGMS NIH HHS T32 GM152284NIH HHS P40 OD010440NIMH NIH HHS R21 MH122961NIMH NIH HHS S10 MH133575NINDS NIH HHS R01 NS083085NINDS NIH HHS R01 NS122784
6 · The paper itselfAbstract
Local protein synthesis in axons and dendrites underpins synaptic plasticity. However, the composition of the protein synthesis machinery in distal neuronal processes and the mechanisms for its activity-driven deployment to local translation sites remain unclear. Here, we employed cryo-electron tomography, volume electron microscopy, and live-cell imaging to identify Ribosome-Associated Vesicles (RAVs) as a dynamic platform for moving ribosomes to distal processes. Stimulation via chemically-induced long-term potentiation causes RAV accumulation in distal sites to drive local translation. We also demonstrate activity-driven changes in RAV generation and dynamics
Indexed as
Cell TraffickingElectron MicroscopyEndoplasmic ReticulumLocal TranslationNeuronsPlasticityRibosome-Associated VesiclesRibosomes
Identifiers
PMID38895376
PMCPMC11185778
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