Evidence map›Paper›PMID 38895345›Full record

ArticlebioRxiv : the preprint server for biology2024

Evidence of RNA polymerase III recruitment and transcription at protein-coding gene promoters.

K C Rajendra, Ruiying Cheng, Sihang Zhou, Simon Lizarazo, Duncan Smith, Kevin Van Bortle

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

K C RajendraCenter for Biophysics and Quantitative Biology, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0009-0006-1675-268X
Ruiying ChengDepartment of Cell and Developmental Biology, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.
Sihang ZhouDepartment of Cell and Developmental Biology, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.
Simon LizarazoDepartment of Molecular and Integrative Physiology, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.
Duncan SmithDepartment of Biology, New York University, New York, NY.
Kevin Van BortleDepartment of Cell and Developmental Biology, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0003-0733-0830

Funding

The development and application of tools to characterize the level and function of RNA polymerase III transcription dynamics during cellular differentiationR00HG010362 · NHGRI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI VAN BORTLE, KEVIN · 2022 to 2024
$747k
NHGRI NIH HHS R00 HG010362
6 · The paper itself

Abstract

RNA polymerase (Pol) I, II, and III are most commonly described as having distinct roles in synthesizing ribosomal RNA (rRNA), messenger RNA (mRNA), and specific small noncoding (nc)RNAs, respectively. This delineation of transcriptional responsibilities is not definitive, however, as evidenced by instances of Pol II recruitment to genes conventionally transcribed by Pol III, including the co-transcription of

Identifiers

PMID38895345
PMCPMC11185800

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.