Evidence map›Paper›PMID 38895306›Full record

ArticlebioRxiv : the preprint server for biology2024

The conformational landscape of fold-switcher KaiB is tuned to the circadian rhythm timescale.

Hannah K Wayment-Steele, Renee Otten, Warintra Pitsawong, Adedolapo M Ojoawo, Andrew Glaser, Logan A Calderone, Dorothee Kern

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Hannah K Wayment-SteeleDepartment of Biochemistry, Brandeis University and Howard Hughes Medical Institute, Waltham, MA, USA.ORCID 0000-0003-4949-2010
Renee OttenDepartment of Biochemistry, Brandeis University and Howard Hughes Medical Institute, Waltham, MA, USA.
Warintra PitsawongDepartment of Biochemistry, Brandeis University and Howard Hughes Medical Institute, Waltham, MA, USA.
Adedolapo M OjoawoDepartment of Biochemistry, Brandeis University and Howard Hughes Medical Institute, Waltham, MA, USA.
Andrew GlaserDepartment of Biochemistry, Brandeis University and Howard Hughes Medical Institute, Waltham, MA, USA.
Logan A CalderoneDepartment of Biochemistry, Brandeis University and Howard Hughes Medical Institute, Waltham, MA, USA.
Dorothee KernDepartment of Biochemistry, Brandeis University and Howard Hughes Medical Institute, Waltham, MA, USA.

Funding

NMR User Program at NMRFAMR24GM141526 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine Anne Henzler-Wildman · 2021 to 2026
$6.4M
NIGMS NIH HHS R24 GM141526
6 · The paper itself

Abstract

How can a single protein domain encode a conformational landscape with multiple stably-folded states, and how do those states interconvert? Here, we use real-time and relaxation-dispersion NMR to characterize the conformational landscape of the circadian rhythm protein KaiB from

Identifiers

PMID38895306
PMCPMC11185700

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.