Evidence map›Paper›PMID 38895233›Full record

ArticlebioRxiv : the preprint server for biology2024

Insula uses overlapping codes for emotion in self and others.

Jiayang Xiao, Joshua A Adkinson, Anusha B Allawala, Garrett Banks, Eleonora Bartoli, Xiaoxu Fan, Madaline Mocchi, Bailey Pascuzzi, Suhruthaa Pulapaka, Melissa C Franch and 13 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Jiayang XiaoDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Joshua A AdkinsonDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Anusha B AllawalaDepartment of Engineering, Brown University, Providence, RI, 02912.
Garrett BanksDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Eleonora BartoliDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Xiaoxu FanDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Madaline MocchiDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Bailey PascuzziDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Suhruthaa PulapakaDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Melissa C FranchDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Sanjay J MathewDepartment of Psychiatry, Baylor College of Medicine, Houston, TX, 77030.
Raissa K MathuraDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
John MyersDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Victoria PirtleDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Nicole R ProvenzaDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Ben ShoftyDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Andrew J WatrousDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Xaq PitkowDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Wayne K GoodmanDepartment of Psychiatry, Baylor College of Medicine, Houston, TX, 77030.
Nader PouratianDepartment of Neurosurgery, University of Texas Southwestern, Dallas, TX, 75390.
Sameer ShethDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Kelly R BijankiDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.
Benjamin Y HaydenDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, 77030.

Funding

Deep brain stimulation for depression using directional current steering an individualized network targetingUH3NS103549 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOODMAN, WAYNE K, POURATIAN, NADER · 2017 to 2025
$8.7M
Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE) while Recording from the BrainUH3NS100549 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI GOODMAN, WAYNE K · 2016 to 2022
$7.8M
Mapping and Modulating the Spatiotemporal dynamics of socio-affective processing.R01MH127006 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI BIJANKI, KELLY ROWE · 2021 to 2025
$3.2M
Neuroethics of aDBS Systems Targeting Neuropsychiatric and Movement DisordersR01MH114854 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI GOODMAN, WAYNE K, LAZARO-MUNOZ, GABRIEL · 2017 to 2020
$2.1M
The human amygdala in social processing: circuits, physiology, behavior, and neuromodulationK01MH116364 · NIMH · EMORY UNIVERSITY · PI BIJANKI, KELLY ROWE · 2018 to 2021
$650k
Modulation of network dynamics across mood states using closed-loop deep brain stimulation for depressionK00MH138156 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Anusha Allawala · 2024 to 2026
$321k
The Effect of Electrical Stimulation on Cognitive Control Networks in Treatment-Resistant DepressionF99NS124181 · NINDS · BROWN UNIVERSITY · PI ALLAWALA, ANUSHA · 2021 to 2022
$95k
NIMH NIH HHS K00 MH138156NIMH NIH HHS K01 MH116364NIMH NIH HHS R01 MH114854NIMH NIH HHS R01 MH127006NINDS NIH HHS F99 NS124181NINDS NIH HHS UH3 NS100549NINDS NIH HHS UH3 NS103549
6 · The paper itself

Abstract

In daily life, we must recognize others' emotions so we can respond appropriately. This ability may rely, at least in part, on neural responses similar to those associated with our own emotions. We hypothesized that the insula, a cortical region near the junction of the temporal, parietal, and frontal lobes, may play a key role in this process. We recorded local field potential (LFP) activity in human neurosurgical patients performing two tasks, one focused on identifying their own emotional response and one on identifying facial emotional responses in others. We found matching patterns of gamma- and high-gamma band activity for the two tasks in the insula. Three other regions (MTL, ACC, and OFC) clearly encoded both self- and other-emotions, but used orthogonal activity patterns to do so. These results support the hypothesis that the insula plays a particularly important role in mediating between experienced vs. observed emotions.

Indexed as

cross-task decodingemotionempathyhuman intracranial recordingsinsulalocal field potentialsvalence

Identifiers

PMID38895233
PMCPMC11185604

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.