Evidence map›Paper›PMID 38895216›Full record

ArticlebioRxiv : the preprint server for biology2024

Comprehensive single cell transcriptomics analysis of murine osteosarcoma uncovers

Alexander Ferrena, Ranxin Zhang, Jichuan Wang, Xiang Yu Zheng, Barlas Göker, Hasibagan Borjihan, Sung-Suk Chae, Yungtai Lo, Hongling Zhao, Edward Schwartz and 5 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Alexander FerrenaInstitute for Clinical and Translational Research, Albert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0002-9578-8683
Ranxin ZhangDepartment of Orthopedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0002-4108-3303
Jichuan WangDepartment of Orthopedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Xiang Yu ZhengDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0001-8656-6598
Barlas GökerDepartment of Orthopedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Hasibagan BorjihanDepartment of Orthopedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Sung-Suk ChaeDepartment of Orthopedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Yungtai LoDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Hongling ZhaoDepartment of Developmental & Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
Edward SchwartzDepartment of Oncology, Albert Einstein College of Medicine, Bronx, NY, USA.
David LoebDepartment of Developmental & Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
Rui YangDepartment of Orthopedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
David GellerDepartment of Orthopedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Deyou ZhengDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0003-4354-5337
Bang HoangDepartment of Orthopedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

Funding

Core-010UL1TR001073 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, SHAMOON, HARRY · 2013 to 2017
$21.3M
Leveraging Tumor Suppressor Inactivation for Osteosarcoma TherapyR01CA255643 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI HOANG, BANG H · 2021 to 2024
$1.7M
NCATS NIH HHS UL1 TR001073NCI NIH HHS R01 CA255643
6 · The paper itself

Abstract

Osteosarcoma (OS) is the most common primary pediatric bone malignancy. One promising new therapeutic target is

Indexed as

immune infiltrationlineage plasticityOsteosarcomasingle-cell RNA-sequencingSKP2tumor heterogeneity

Identifiers

PMID38895216
PMCPMC11185585

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.