Evidence map›Paper›PMID 38895118›Full record

ArticleFrontiers in immunology2024

The extracellular serine protease from

Goran Abdurrahman, Rebecca Pospich, Leif Steil, Manuela Gesell Salazar, Juan José Izquierdo González, Nicole Normann, Daniel Mrochen, Christian Scharf, Uwe Völker, Thomas Werfel and 3 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Frontiers in immunology · 2026
    Article
  3. Life (Basel, Switzerland) · 2025
    Article
  4. CommensalFrontiers in immunology · 2025
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Goran AbdurrahmanInstitute of Immunology, University Medicine Greifswald, Greifswald, Germany.
Rebecca PospichDepartment of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.
Leif SteilDepartment of Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Manuela Gesell SalazarDepartment of Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Juan José Izquierdo GonzálezInstitute of Immunology, University Medicine Greifswald, Greifswald, Germany.
Nicole NormannInstitute of Immunology, University Medicine Greifswald, Greifswald, Germany.
Daniel MrochenInstitute of Immunology, University Medicine Greifswald, Greifswald, Germany.
Christian ScharfDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medicine Greifswald, Greifswald, Germany.
Uwe VölkerDepartment of Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Thomas WerfelDepartment of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.
Barbara M BrökerInstitute of Immunology, University Medicine Greifswald, Greifswald, Germany.
Lennart M RoesnerDepartment of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.
Lidia Gómez-GascónInstitute of Immunology, University Medicine Greifswald, Greifswald, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disease with skin barrier defects and a misdirected type 2 immune response against harmless antigens. The skin microbiome in AD is characterized by a reduction in microbial diversity with a dominance of staphylococci, including Objective: To assess whether Methods: To identify candidate allergens, we analyzed the binding of human serum IgG4, as a surrogate of IgE, to Results: We identified Esp as the dominant candidate allergen of Conclusion: The extracellular serine protease Esp of

Indexed as

Dermatitis, AtopicImmunoglobulin ESerine ProteasesStaphylococcus epidermidisAdultAllergensBacterial ProteinsCytokinesFemaleHumansImmunoglobulin GInterleukin-33MaleMiddle AgedT-LymphocytesAllergensBacterial ProteinsCytokinesImmunoglobulin EImmunoglobulin GInterleukin-33Serine Proteasesallergyatopic dermatitisEspIgEproteaseStaphylococcus epidermidisTh2 cells

Identifiers

PMID38895118
PMCPMC11183529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.