Evidence map›Paper›PMID 38895085›Full record

ArticleEJHaem2024

Treatment sequencing and impact of number of treatment lines on survival in follicular lymphoma: A national population-based study.

Tove Wästerlid, Caroline E Dietrich, Anna Oksanen, Linn Deleskog Spångberg, Björn E Wahlin, Gunilla Enblad, Per-Ola Andersson, Eva Kimby, Karin E Smedby

Abstract read
In one paragraph

Article in EJHaem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. In pursuit of a functional cure for follicular lymphoma.Hematology. American Society of Hematology. Education Program · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tove WästerlidClinical Epidemiology Division Department of Medicine Solna Karolinska Institutet Stockholm Sweden.ORCID https://orcid.org/0000-0002-4281-0349
Caroline E DietrichClinical Epidemiology Division Department of Medicine Solna Karolinska Institutet Stockholm Sweden.ORCID https://orcid.org/0000-0001-8231-8183
Anna OksanenDepartment of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden.
Linn Deleskog SpångbergClinical Epidemiology Division Department of Medicine Solna Karolinska Institutet Stockholm Sweden.
Björn E WahlinDepartment of Hematology Karolinska University Hospital Stockholm Sweden.ORCID https://orcid.org/0000-0003-3566-8847
Gunilla EnbladDepartment of Immunology, Genetics and Pathology Experimental and Clinical Oncology, Uppsala University Uppsala Sweden.
Per-Ola AnderssonSection for Hematology, Oncology and Lung medicine Södra Älvsborg Hospital Borås Sweden.
Eva KimbyUnit of Hematology, Department of Medicine Huddinge Karolinska Institutet Stockholm Sweden.
Karin E SmedbyClinical Epidemiology Division Department of Medicine Solna Karolinska Institutet Stockholm Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Follicular lymphoma (FL) is a clinically heterogeneous disease. The need for treatment, treatment sequencing, number of treatment lines, and its association with survival have not been described in a population-based setting. We identified all patients diagnosed with FL in the Swedish Lymphoma register from 2007 to 2014, followed until 2020, with detailed data on progression/relapse, transformation, and 2nd and further lines of therapy. During a median follow-up of 6.8 years, 1226 patients (69%) received 1st systemic treatment, 358 patients (20%) were managed with watch-and-wait (WaW) only, and 188 (10%) patients were treated with radiotherapy and did not require additional therapy during the study period. Among patients starting systemic treatment, 496 (40%), 224 (18%), and 88 (7%) received 2nd-, 3rd-, or 4th-line therapy, respectively. The 10-year cause-specific cumulative incidence of transformation was 13%. Among patients managed with 1

Indexed as

follicular lymphomaPOD24population‐basedtreatment sequencing

Identifiers

PMID38895085
PMCPMC11182409

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.