Evidence map›Paper›PMID 38895079›Full record

ArticleEJHaem2024

Severe acute respiratory syndrome coronavirus 2 infection in patients with hematological malignancies in the Omicron era: Respiratory failure, need for mechanical ventilation and mortality in seronegative and seropositive patients.

Erica Franceschini, Valentina Menozzi, Vera Todisco, Mariachiara Pellegrino, Samuele Cantergiani, Andrea Dessilani, Anna Spadoni, Federico Romani, Alice Mazzocchi, Antonella Santoro and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJHaem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Erica FranceschiniDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.ORCID https://orcid.org/0000-0001-6922-5759
Valentina MenozziDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.ORCID https://orcid.org/0009-0003-5739-6528
Vera TodiscoDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Mariachiara PellegrinoDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Samuele CantergianiDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Andrea DessilaniDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Anna SpadoniDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Federico RomaniDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Alice MazzocchiDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Antonella SantoroDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Marianna MeschiariDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Adriana CervoDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Andrea GilioliDepartment of Medical and Surgical Sciences Section of Hematology University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Francesca BettelliDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Giulia Fregni-SerpiniDepartment of Laboratory Medicine Molecular Virology and Microbiology Unit AOU Policlinico di Modena Modena Italy.
Antonella GrottolaDepartment of Laboratory Medicine Molecular Virology and Microbiology Unit AOU Policlinico di Modena Modena Italy.
Anna CandoniDepartment of Medical and Surgical Sciences Section of Hematology University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Giovanni GuaraldiDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.
Mario SartiDepartment of Laboratory Medicine Clinical Microbiology Laboratory Modena Italy.
Mario LuppiDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.ORCID https://orcid.org/0000-0002-0373-1154
Cristina MussiniDepartment of Surgical, Medical, Dental, and Morphological Sciences, University of Modena and Reggio Emilia, Infectious Disease Clinic University of Modena and Reggio Emilia AOU Policlinico di Modena Modena Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with hematological malignancies (HM) have a high risk of severe coronavirus disease 2019 (COVID-19), also in the Omicron period. Material and methods: Retrospective single-center study including HM patients with severe acute respiratory syndrome Coronavirus 2 (SARS-CoV2) infection from January 2022 to March 2023. Study outcomes were respiratory failure (RF), mechanical ventilation (MV), and COVID-related mortality, comparing patients according to SARS-CoV2 serology. Results: Note that, 112 patients were included: 39% had negative SARS-CoV2 serology. Seronegative were older (71.5 vs. 65.0 years, Conclusions: : HM patients with negative SARS-CoV2 serology, despite vaccinations and previous infections, have worse clinical outcomes compared to seropositive patients in the Omicron era. The use of serology for SARS-CoV2 diagnosis could be an easy tool to identify patients prone to developing complications.

Indexed as

COVID‐19hematological malignanciesserostatus

Identifiers

PMID38895079
PMCPMC11182402

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.