Evidence map›Paper›PMID 38895024›Full record

ArticleLaryngoscope investigative otolaryngology2024

Radiofrequency ablation compared to surgery for thyroid nodules: A case for office based treatment.

Alex K F Lee, Thomas Hui, Zenon W C Yeung, Eddy W Y Wong, Jason Y K Chan, Eric H L Lau

Abstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cost-Effectiveness of Radiofrequency Ablation for Benign Non-Functioning Thyroid Nodules: A Systematic Review.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alex K F LeeDepartment of Otorhinolaryngology, Head and Neck Surgery Tseung Kwan O Hospital Hong Kong Hong Kong.ORCID https://orcid.org/0000-0003-1791-8750
Thomas HuiDepartment of Otorhinolaryngology, Head and Neck Surgery Tseung Kwan O Hospital Hong Kong Hong Kong.
Zenon W C YeungDepartment of Otorhinolaryngology, Head and Neck Surgery Tseung Kwan O Hospital Hong Kong Hong Kong.ORCID https://orcid.org/0000-0003-4643-6240
Eddy W Y WongDepartment of Otorhinolaryngology, Head and Neck Surgery Prince of Wales Hospital Hong Kong Hong Kong.ORCID https://orcid.org/0000-0001-9852-5080
Jason Y K ChanDepartment of Otorhinolaryngology, Head and Neck Surgery Prince of Wales Hospital Hong Kong Hong Kong.ORCID https://orcid.org/0000-0002-9480-4637
Eric H L LauDepartment of Otorhinolaryngology, Head and Neck Surgery Prince of Wales Hospital Hong Kong Hong Kong.ORCID https://orcid.org/0000-0003-3249-6496

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We aim to evaluate the safety and effectiveness of radiofrequency ablation (RFA) for benign thyroid nodules by ENT surgeons and to compare it to conventional hemithyroidectomy in the public healthcare, operating theater contained setting. Methods: 50 patients who underwent a single session of RFA for symptomatic benign thyroid nodules in Prince of Wales Hospital and Tseung Kwan O Hospital in Hong Kong from 2020 to 2022 were evaluated. Objective outcomes including nodule volume, volume reduction rate (VRR) and complications were recorded. Subjective response in the form of a 0-10 point scale for patient symptoms including obstructive, cosmetic, pain and satisfaction scores were collected. Results: Significant reduction in mean VRR was found at 3, 6 and 12 months post treatment, accompanied by a significant reduction in the mean obstructive and cosmetic symptom scores. Comparing with conventional hemithyroidectomy, the RFA group had a significantly shorter mean procedure time and lower rate of complications. Estimated cost to patient for RFA was found to be less than half of that of hemithyroidectomy. Conclusion: RFA is a safe and effective treatment modality for benign thyroid nodules by ENT surgeons with advantages of being a scarless local anesthetic procedure with shorter procedure time, lower complication rate and lower cost to patient compared to hemithyroidectomy. In Hong Kong, where most of the population is treated in the public sector, there are limited resources, often with high caseload burden and long operation waiting times. Therefore, RFA is an office-based treatment that serves as a valuable alternative to hemithyroidectomy for benign nodules, especially in lower resource settings. Level of evidence: 3.

Indexed as

hemithyroidectomyRFAthyroid nodules

Identifiers

PMID38895024
PMCPMC11184567

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.