Evidence map›Paper›PMID 38895023›Full record

ArticleGraphic medicine review2024

The Alcohol Flush Response.

Isabel Moh, Daniel Simon, Eric R Gross

Abstract read
In one paragraph

Article in Graphic medicine review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Isabel MohUniversity of Nevada, Reno, NV USA.
Daniel SimonAnesthesiology, Perioperative and Pain Medicine, Stanford Medicine, Stanford University, Stanford, CA USA.
Eric R GrossAnesthesiology, Perioperative and Pain Medicine, Stanford Medicine, Stanford University, Stanford, CA USA.

Funding

Precision Targeting of Aldehyde Pathways for Patients Requiring AnesthesiaR35GM119522 · NIGMS · STANFORD UNIVERSITY · PI Eric Richard Gross · 2016 to 2026
$5.1M
Rho-mediated Signaling in Lung Endothelial Cells Induced by Neutrophil AdhesionR01HL114388 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BURRIDGE, KEITH, DOERSCHUK, CLAIRE M · 2012 to 2016
$3.0M
E-cigarette aerosol effects on the cardiovascular system in rodentsR01HL144388 · NHLBI · STANFORD UNIVERSITY · PI GROSS, ERIC RICHARD · 2018 to 2021
$1.9M
NHLBI NIH HHS R01 HL114388NHLBI NIH HHS R01 HL144388NIGMS NIH HHS R35 GM119522
6 · The paper itself

Abstract

Nearly 540 million people world-wide have facial flushing and an increased heart rate after consuming alcohol. Known as the alcohol flushing response, this reaction to alcohol is a result of a genetic variant in an enzyme aldehyde dehydrogenase 2 (ALDH2), known as ALDH2*2. Mainly carried by those of East Asian descent, the genetic variant is likely the most common genetic variant carried in the world. Carrying this ALDH2*2 genetic variant has important health implications with respect cancer risk which is increased when carriers of the ALDH2*2 genetic variant frequently use of alcohol or tobacco products. This comic explains the alcohol flush response and the health risks associated with alcohol and tobacco use for those who carry an ALDH2*2 variant.

Identifiers

PMID38895023
PMCPMC11185044

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.