Evidence map›Paper›PMID 38894925›Full record

ArticleACS medicinal chemistry letters2024

Novel 2,4-Dichloro-5-sulfamoylbenzoic Acid Oxime Esters: First Studies as Potential Human Carbonic Anhydrase Inhibitors.

Jaydeo T Kilbile, Suryakant B Sapkal, Gioele Renzi, Ilaria D'Agostino, Luigi Cutarella, Mattia Mori, Barbara De Filippis, Imadul Islam, Maria Luisa Massardi, Elena Somenza and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jaydeo T KilbileDepartment of Chemistry, School of Basic and Applied Sciences, MGM University, Chhatrapati Sambhajinagar, 431003 Maharashtra, India.
Suryakant B SapkalDepartment of Chemistry, School of Basic and Applied Sciences, MGM University, Chhatrapati Sambhajinagar, 431003 Maharashtra, India.
Gioele RenziNEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Sesto Fiorentino, 50019 Florence, Italy.ORCID https://orcid.org/0009-0008-9109-030X
Ilaria D'AgostinoNEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Sesto Fiorentino, 50019 Florence, Italy.ORCID https://orcid.org/0000-0002-4870-7326
Luigi CutarellaDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Mattia MoriDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.ORCID https://orcid.org/0000-0003-2398-1254
Barbara De FilippisDepartment of Pharmacy "G. d'Annunzio", University of Chieti-Pescara, 66100 Chieti, Italy.
Imadul IslamKing Abdullah International Medical Research Center (KAIMRC), King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Riyadh 14811, Saudi Arabia.
Maria Luisa MassardiDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Elena SomenzaDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Roberto RoncaDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Yasinalli TamboliKing Abdullah International Medical Research Center (KAIMRC), King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Riyadh 14811, Saudi Arabia.ORCID https://orcid.org/0000-0002-5161-0170
Fabrizio CartaNEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Sesto Fiorentino, 50019 Florence, Italy.ORCID https://orcid.org/0000-0002-1141-6146
Claudiu T SupuranNEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Sesto Fiorentino, 50019 Florence, Italy.ORCID https://orcid.org/0000-0003-4262-0323

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a focused library of oxime ester derivatives of 2,4-dichloro-5-sulfamoylbenzoic acid (lasamide) containing Schiff bases was synthesized and tested

Identifiers

PMID38894925
PMCPMC11181484

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.