ArticleFrontiers in oncology2024
Magnetic resonance image-guided adaptive radiotherapy enables safe CTV-to-PTV margin reduction in prostate cancer: a cine MRI motion study.
Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Relationship between rectal bleeding and radiation delivery time in intensity-modulated radiotherapy for localized prostate cancer: a preliminary study.Journal of radiation research · 2026Article
- Evaluating the role of plan complexity metrics in online adaptive radiotherapy for pancreatic cancer patients.Medical physics · 2026Article
- Magnetic Resonance Guided Radiation Therapy (MRgRT) Prostate Motion and Margins.Journal of medical radiation sciences · 2026Article
- Prospective controlled study comparing patient-reported outcomes after daily online adaptive radiotherapy or conventional IGRT in patients with prostate cancer.Clinical and translational radiation oncology · 2026Article
- MR-Linac-Based SBRT for Prostate Cancer: Dosimetric Benefits for Urethral Sparing Compared to VMAT and Tomotherapy.Cancers · 2026Article
- Effect of respiration-induced motion on a three-dimensional magnetic resonance imaging-based adaptive radiotherapy workflow in a 1.5T magnetic resonance linear accelerator.Quantitative imaging in medicine and surgery · 2025Article
- Ultrahypofractionated radiotherapy for localised prostate cancer: The impact of daily MRI-guided adaptive radiotherapy on delivered dose.Clinical and translational radiation oncology · 2025Article
- First clinical application of Comprehensive Motion Management with 1.5T MR-linac on prostate cancer patients treated with radiotherapy: technical aspects and suggested workflow recommendations.La Radiologia medica · 2025Article
- To irradiate or to wait: practical considerations when planning for stereotactic radiosurgery for kidney tumors using magnetic resonance-guided online adaptive radiotherapy.Radiation oncology journal · 2025Article
- From CBCT to MR-Linac in Image-Guided Prostate Cancer Radiotherapy Towards Treatment Personalization.Current oncology (Toronto, Ont.) · 2025Review
- Magnetic resonance-guided adaptive stereotactic radiotherapy in prostate cancer patients: a systematic literature review.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025Review
- Feasibility and time gain of implementing artificial intelligence-based delineation tools in daily magnetic resonance image-guided adaptive prostate cancer radiotherapy.Physics and imaging in radiation oncology · 2025Article
- Article
- Development and Validation of a Magnetic Resonance Imaging-Guided Adaptive Radiotherapy Workflow for Long, Continuous Planning Target Volumes.Technology in cancer research & treatmentArticle
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Authors and funding
8 authors.
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Abstract
Introduction: We aimed to establish if stereotactic body radiotherapy to the prostate can be delivered safely using reduced clinical target volume (CTV) to planning target volume (PTV) margins on the 1.5T MR-Linac (MRL) (Elekta, Stockholm, Sweden), in the absence of gating. Methods: Cine images taken in 3 orthogonal planes during the delivery of prostate SBRT with 36.25 Gray (Gy) in 5 fractions on the MRL were analysed. Using the data from 20 patients, the percentage of radiotherapy (RT) delivery time where the prostate position moved beyond 1, 2, 3, 4 and 5 mm in the left-right (LR), superior-inferior (SI), anterior-posterior (AP) and any direction was calculated. Results: The prostate moved less than 3 mm in any direction for 90% of the monitoring period in 95% of patients. On a per-fraction basis, 93% of fractions displayed motion in all directions within 3 mm for 90% of the fraction delivery time. Recurring motion patterns were observed showing that the prostate moved with shallow drift (most common), transient excursions and persistent excursions during treatment. Conclusion: A 3 mm CTV-PTV margin is safe to use for the treatment of 5 fraction prostate SBRT on the MRL, without gating. In the context of gating this work suggests that treatment time will not be extensively lengthened when an appropriate gating window is applied.
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