Evidence map›Paper›PMID 38894859›Full record

ArticleExposure and health2022

Heavy Metal(loid) Body Burden in Environmentally Exposed Children With and Without Internalizing Behavior Problems.

Kristina M Zierold, John V Myers, Guy N Brock, Charlie H Zhang, Clara G Sears, Lonnie Sears

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Exposure and health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kristina M ZieroldDepartment of Environmental Health Sciences, School of Public Health, University of Alabama at Birmingham, RPHB 534C, 1720 2nd Ave S, Birmingham, AL 35294‑0022, USA.ORCID 0000-0002-9246-0404
John V MyersDepartment of Biomedical Informatics and Center for Biostatistics, The Ohio State University, Columbus, OH, USA.
Guy N BrockDepartment of Biomedical Informatics and Center for Biostatistics, The Ohio State University, Columbus, OH, USA.
Charlie H ZhangDepartment of Geographic & Environmental Sciences, University of Louisville, Louisville, KY, USA.
Clara G SearsDepartment of Environmental Medicine, University of Louisville, Louisville, KY, USA.
Lonnie SearsDepartment of Pediatrics, University of Louisville, Louisville, KY, USA.

Funding

Coal Ash and Neurobehavioral Symptoms in Children Aged 6-14 Years Old.R01ES024757 · NIEHS · UNIVERSITY OF LOUISVILLE · PI ZIEROLD, KRISTINA MARIE · 2015 to 2019
$2.8M
NIEHS NIH HHS R01 ES024757
6 · The paper itself

Abstract

The prevalence of internalizing behavior disorders in children is increasing. Reasons for increasing anxiety and depression include several factors with a less studied consideration being the potential neurotoxic effects of environmental exposures. One group at risk for environmental exposures is children living near coal-burning power plants with coal ash storage facilities. Multivariate logistic regression was used to assess the relationship between metal(loid) exposures and internalizing behaviors in children aged 6-14 years. Metal(loid)s in nail samples were determined by Proton-Induced X-ray Emission and internalizing behavior problems were obtained from the parent ratings on the Child Behavior Checklist. Results indicated that concentrations of metal(loid)s in nails differ between children with internalizing behaviors and without internalizing behaviors. Logistic regression models suggested that exposure to zinc and imputed zirconium were associated with internalizing behaviors in children. However, when a sex-metal(loid) interaction term was included, none of the metal(loid)s were associated with internalizing behaviors indicating a role of sex differences in neurotoxicity with zinc and copper showing effects only for males. In all models, greater exposure to traffic was associated with internalizing behaviors. Zinc has previously been shown to increase risk for mental health problems, while zirconium has received less attention. Out findings indicate that environmental exposures of zinc and zirconium deserve further attention in studies of childhood internalizing disorders.

Indexed as

BiomarkersChildren’s environmental healthCoal ashHeavy metal(loid)sInternalizing behaviorsNeurotoxicity

Identifiers

PMID38894859
PMCPMC11185413

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.