Evidence map›Paper›PMID 38894855›Full record

ArticleResuscitation plus2024

Facilitators and barriers to the delivery of the PARAMEDIC2 trial.

Helen Pocock, Nigel Rees, Imogen Gunson, Mark Docherty, Karl Charlton, Michelle Jackson, Charlotte Scomparin, Ed England, Rachael Fothergill

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Resuscitation plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Helen PocockSouth Central Ambulance Service NHS Foundation Trust, UK.
Nigel ReesWelsh Ambulance Services NHS Trust, UK.
Imogen GunsonWest Midlands Ambulance Service University NHS Foundation Trust, UK.
Mark DochertyWest Midlands Ambulance Service University NHS Foundation Trust, UK.
Karl CharltonNorth East Ambulance Service NHS Foundation Trust, UK.
Michelle JacksonNorth East Ambulance Service NHS Foundation Trust, UK.
Charlotte ScomparinWarwick Clinical Trials Unit, University of Warwick, UK.
Ed EnglandSouth Central Ambulance Service NHS Foundation Trust, UK.
Rachael FothergillLondon Ambulance Service NHS Trust, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: PARAMEDIC2 was a medicines trial comparing adrenaline with placebo in out-of-hospital cardiac arrest (OHCA). At the time, United Kingdom (UK) Emergency Medical Systems (EMS) were inexperienced in delivering such research. Aim: To identify barriers and facilitators to delivery of the PARAMEDIC2 (Adrenaline) trial by five UK NHS EMS. Methods: This qualitative study took a grounded theory approach to thematic analysis of workshop data. Members of the trial teams from each service attended a workshop in November 2018 and discussed their experiences in answer to two prompt questions. Data were coded and themes presented. Results: Three main themes were identified: Conclusion: Barriers to trial delivery included infrequent exposure to the condition of interest and lack of continuity in research paramedic roles. Facilitators identified included flexibility of the research protocol, and organisational investment in the development of research paramedics.Participating in PARAMEDIC2 was challenging for the EMS involved, but ultimately strengthened their research culture.

Indexed as

Cardiopulmonary ResuscitationMethodologyOut-of-hospital Cardiac ArrestRandomised Controlled TrialTrial design

Identifiers

PMID38894855
PMCPMC11184479

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.