Evidence map›Paper›PMID 38894708›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2024

FNPC-SAM: Uncertainty-Guided False Negative/Positive Control for SAM on Noisy Medical Images.

Xing Yao, Han Liu, Dewei Hu, Daiwei Lu, Ange Lou, Hao Li, Ruining Deng, Gabriel Arenas, Baris Oguz, Nadav Schwartz and 2 more

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. From Geometry to Intensity: A Coarse-to-Fine Pipeline for Unsupervised 3D Ultrasound Stitching.Proceedings of SPIE--the International Society for Optical Engineering · 2026
    Article
  3. SEGMENTATION CONFIDENCE FOR ARBITRARY CNNS.Proceedings. IEEE International Symposium on Biomedical Imaging · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. PRISM Lite: A lightweight model for interactive 3D placenta segmentation in ultrasound.Proceedings of SPIE--the International Society for Optical Engineering · 2025
    Article
  8. PRISM: A Promptable and Robust Interactive Segmentation Model with Visual Prompts.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xing YaoDept. of Computer Science, Vanderbilt University, Nashville, TN, USA.
Han LiuDept. of Computer Science, Vanderbilt University, Nashville, TN, USA.
Dewei HuDept. of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, USA.
Daiwei LuDept. of Computer Science, Vanderbilt University, Nashville, TN, USA.
Ange LouDept. of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, USA.
Hao LiDept. of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, USA.
Ruining DengDept. of Computer Science, Vanderbilt University, Nashville, TN, USA.
Gabriel ArenasDept. of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA, USA.
Baris OguzDept. of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA, USA.
Nadav SchwartzDept. of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA, USA.
Brett C ByramDept. of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
Ipek OguzDept. of Computer Science, Vanderbilt University, Nashville, TN, USA.

Funding

NRSA Training CoreTL1TR001880 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI MEAGHER, EMMA ANNE · 2016 to 2025
$10.0M
A placenta-based strategy for improved clinical prediction of fetal growth trajectory using automated image analysis of placental morphology and vascularityR01HD109739 · NICHD · VANDERBILT UNIVERSITY · PI Ipek Oguz, Nadav Schwartz · 2022 to 2026
$3.1M
Ultrasound clutter and noise improvements applied to echocardiographic left atrial appendage visualizationR01HL156034 · NHLBI · VANDERBILT UNIVERSITY · PI BYRAM, BRETT C, EAGLE, SUSAN · 2021 to 2024
$2.3M
NCATS NIH HHS TL1 TR001880NHLBI NIH HHS R01 HL156034NICHD NIH HHS R01 HD109739
6 · The paper itself

Abstract

The Segment Anything Model (SAM) is a recently developed all-range foundation model for image segmentation. It can use sparse manual prompts such as bounding boxes to generate pixel-level segmentation in natural images but struggles in medical images such as low-contrast, noisy ultrasound images. We propose a refined test-phase prompt augmentation technique designed to improve SAM's performance in medical image segmentation. The method couples multi-box prompt augmentation and an aleatoric uncertainty-based false-negative (FN) and false-positive (FP) correction (FNPC) strategy. We evaluate the method on two ultrasound datasets and show improvement in SAM's performance and robustness to inaccurate prompts, without the necessity for further training or tuning. Moreover, we present the Single-Slice-to-Volume (SS2V) method, enabling 3D pixel-level segmentation using only the bounding box annotation from a single 2D slice. Our results allow efficient use of SAM in even noisy, low-contrast medical images. The source code has been released at: https://github.com/MedICL-VU/FNPC-SAM.

Indexed as

kidneymedical image segmentationplacentaprompt engineeringSAMultrasounduncertaintyzero-shot

Identifiers

PMID38894708
PMCPMC11182739

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.