Evidence map›Paper›PMID 38893723›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Dynamic Perviousness: A Novel Imaging Marker for Predicting Mechanical Thrombectomy Outcomes in Acute Ischemic Stroke.

Daniel F Toth, Gergely Bertalan, Priska Heinz, Jawid Madjidyar, Patrick Thurner, Tilman Schubert, Zsolt Kulcsar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Advances in Cerebrovascular Imaging and Interventions.Diagnostics (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel F TothDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zürich, 8091 Zürich, Switzerland.
Gergely BertalanDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zürich, 8091 Zürich, Switzerland.ORCID 0009-0000-3986-9844
Priska HeinzDepartment of Biostatistics, Epidemiology, Biostatistics and Prevention Institute, University of Zürich, 8001 Zürich, Switzerland.
Jawid MadjidyarDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zürich, 8091 Zürich, Switzerland.
Patrick ThurnerDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zürich, 8091 Zürich, Switzerland.
Tilman SchubertDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zürich, 8091 Zürich, Switzerland.
Zsolt KulcsarDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zürich, 8091 Zürich, Switzerland.ORCID 0000-0002-6805-5150

Funding

Iten-Kohaut-Foundation in Switzerland 0
6 · The paper itself

Abstract

backgroundThe predictive value of thrombus standard perviousness (SP) in acute ischemic stroke (AIS) for the technical success rates of mechanical thrombectomy (MT) or functional outcomes is not yet conclusive. We investigated the relationship between dynamic perviousness (DP) and revascularization results using time-dependent enhancement curve types determined with computed tomography (CT).

methodsA retrospective analysis of 137 AIS patients was performed. DP was calculated as the thrombus attenuation increase (TAI) using three time points and categorized into four groups: (1) no enhancement (CNE); (2) late enhancement (CLE); (3) early enhancement with washout (CW); (4) early enhancement without washout (CNW). Associations with the technical success rate and functional outcomes were assessed.

resultsLate enhancement (CLE) had approximately two times higher odds for successful MT as compared to clots with other enhancement dynamics. The odds ratios (logistic regression model with CNW as the reference) for the TICI III scores were 4.04 (

conclusionsThrombi with late enhancement patterns showed a higher revascularization rate and better outcomes as compared to clots with early uptake or no washout.

Indexed as

acute ischemic strokecomputed tomographydynamic perviousness of thrombimechanical thrombectomy

Identifiers

PMID38893723
PMCPMC11171946

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.