Evidence map›Paper›PMID 38893635›Full record

ArticleDiagnostics (Basel, Switzerland)2024

White Matter Hyperintensity in Patients with Sudden Sensorineural Hearing Loss.

Mehdi Abouzari, Arash Abiri, Karen Tawk, Cynthia Tsang, Beenish Patel, Avissa Khoshsar, Hamid R Djalilian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Migraine Features in Patients With Sudden Sensorineural Hearing Loss.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mehdi AbouzariDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, CA 92697, USA.ORCID 0000-0002-3585-698X
Arash AbiriDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, CA 92697, USA.
Karen TawkDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, CA 92697, USA.ORCID 0009-0008-0054-8718
Cynthia TsangDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, CA 92697, USA.
Beenish PatelDepartment of Biomedical Engineering, University of California, Irvine, CA 92697, USA.
Avissa KhoshsarDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, CA 92697, USA.
Hamid R DjalilianDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, CA 92697, USA.

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
NRSA Training CoreTL1TR001415 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI CAIOZZO, VINCENT JAMES, HEAD, ELIZABETH · 2015 to 2023
$4.2M
NCATS NIH HHS TL1 TR001415NCATS NIH HHS TL1TR001415NCATS NIH HHS UL1 TR001414NCRR NIH HHS TL1TR001415
6 · The paper itself

Abstract

objectiveTo compare white matter hyperintensities (WMHs) on T2-weighted magnetic resonance imaging (MRI) of patients with sudden sensorineural hearing loss (SSNHL) and analyze subpopulations with age-matched controls.

methodsT2-weighted MRI scans of 150 patients with SSNHL were assessed for WMHs and compared with the data of 148 healthy age-matched adults. Assessments of WMHs included independent grading of deep white matter hyperintensities (DWMHs) and periventricular hyperintensities (PVHs). WMH severity was visually rated using the Fazekas and Mirsen scales by two independent observers.

resultsFazekas grades for PVHs (

conclusionsPatients with sudden hearing loss have a much higher likelihood of having periventricular and deep white matter hyperintensities compared to age-matched controls. These findings indicate that sudden hearing loss patients are more likely to have microvascular changes in the brain, which may indicate a vascular and/or migraine origin to sudden sensorineural hearing loss.

Indexed as

Fazekas scalemagnetic resonance imagingMirsen scalesudden sensorineural hearing losswhite matter hyperintensity

Identifiers

PMID38893635
PMCPMC11171904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.