Evidence map›Paper›PMID 38893460›Full record

ReviewMolecules (Basel, Switzerland)2024

Nanomaterials in Drug Delivery: Strengths and Opportunities in Medicine.

Chinedu O Egwu, Chinyere Aloke, Kenneth T Onwe, Chukwunalu Igbudu Umoke, Joseph Nwafor, Robert A Eyo, Jennifer Adaeze Chukwu, Godswill O Ufebe, Jennifer Ladokun, David Tersoo Audu and 3 more

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Review
  2. Toxicity of nanostructures in drug delivery applications.Pharmaceutical science advances · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Nanocarrier-mediated CRISPR-Cas delivery: a novel approach against antibiotic-resistant superbugs.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chinedu O EgwuMedical Research Council, London School of Hygiene and Tropical Medicine, Banjul 220, The Gambia.ORCID 0000-0003-3408-5471
Chinyere AlokeMedical Biochemistry Department, College of Medicine, Alex-Ekwueme Federal University Ndufu-Alike, P.M.B. 1010, Ikwo 482131, Nigeria.ORCID 0000-0002-8929-6754
Kenneth T OnweAnatomy Department, College of Medicine, Alex-Ekwueme Federal University Ndufu-Alike, P.M.B. 1010, Ikwo 482131, Nigeria.
Chukwunalu Igbudu UmokeAnatomy Department, College of Medicine, Alex-Ekwueme Federal University Ndufu-Alike, P.M.B. 1010, Ikwo 482131, Nigeria.
Joseph NwaforAnatomy Department, College of Medicine, Alex-Ekwueme Federal University Ndufu-Alike, P.M.B. 1010, Ikwo 482131, Nigeria.
Robert A EyoMedical Biochemistry Department, College of Medicine, Alex-Ekwueme Federal University Ndufu-Alike, P.M.B. 1010, Ikwo 482131, Nigeria.
Jennifer Adaeze ChukwuWorld Health Organization, United Nations House Plot 617/618 Central Area District, P.M.B. 2861, Abuja 900211, Nigeria.ORCID 0000-0002-1003-4664
Godswill O UfebeMedical Biochemistry Department, College of Medicine, Alex-Ekwueme Federal University Ndufu-Alike, P.M.B. 1010, Ikwo 482131, Nigeria.
Jennifer LadokunSociety for Family Health, 20 Omotayo Ojo Street, Allen, Ikeja 100246, Nigeria.
David Tersoo AuduUNICEF Sokoto Field Office, 2 Rahamaniyya Street, Off Sama Road, Sokoto 840224, Nigeria.
Anthony O AgwuMedical Biochemistry Department, College of Medicine, Alex-Ekwueme Federal University Ndufu-Alike, P.M.B. 1010, Ikwo 482131, Nigeria.
David Chukwu ObasiDepartment of Medical Biochemistry, David Umahi Federal University of Health Sciences, Uburu 491105, Nigeria.
Chukwuemeka O OkoroDepartment of Medical Biochemistry, David Umahi Federal University of Health Sciences, Uburu 491105, Nigeria.ORCID 0000-0001-7797-4645

Funding

World Health Organization 001
6 · The paper itself

Abstract

There is a myriad of diseases that plague the world ranging from infectious, cancer and other chronic diseases with varying interventions. However, the dynamism of causative agents of infectious diseases and incessant mutations accompanying other forms of chronic diseases like cancer, have worsened the treatment outcomes. These factors often lead to treatment failure via different drug resistance mechanisms. More so, the cost of developing newer drugs is huge. This underscores the need for a paradigm shift in the drug delivery approach in order to achieve desired treatment outcomes. There is intensified research in nanomedicine, which has shown promises in improving the therapeutic outcome of drugs at preclinical stages with increased efficacy and reduced toxicity. Regardless of the huge benefits of nanotechnology in drug delivery, challenges such as regulatory approval, scalability, cost implication and potential toxicity must be addressed via streamlining of regulatory hurdles and increased research funding. In conclusion, the idea of nanotechnology in drug delivery holds immense promise for optimizing therapeutic outcomes. This work presents opportunities to revolutionize treatment strategies, providing expert opinions on translating the huge amount of research in nanomedicine into clinical benefits for patients with resistant infections and cancer.

Indexed as

Drug Delivery SystemsNanomedicineNanostructuresAnimalsHumansNanotechnologyNeoplasmscancercontrolled-releasehigh-efficacyinfectious diseaseslow-toxicitynanotechnologytargeted-deliverytreatment

Identifiers

PMID38893460
PMCPMC11173789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.