Evidence map›Paper›PMID 38893386›Full record

ArticleMolecules (Basel, Switzerland)2024

New Triazole-Isoxazole Hybrids as Antibacterial Agents: Design, Synthesis, Characterization, In Vitro, and In Silico Studies.

Rachid Bouzammit, Salim Belchkar, Mohamed El Fadili, Youssra Kanzouai, Somdutt Mujwar, Mohammed M Alanazi, Mohammed Chalkha, Asmae Nakkabi, Mohamed Bakhouch, Emese Gal and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Cytotoxic Triterpenes from Argan Pulp (Molecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Frontiers in chemistry · 2025
    Article
  4. Essential Oil FromAdvances in pharmacological and pharmaceutical sciences · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Frontiers in chemistry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rachid BouzammitEngineering Laboratory of Organometallic and Molecular Materials and Environment, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Atlas, Fez 30000, Morocco.
Salim BelchkarLaboratory of Epidemiology and Research in Health Sciences, Faculty of Medicine, Pharmacy and Dentistry, University Sidi Mohammed Ben Abdellah, Fez 30070, Morocco.ORCID 0000-0002-4750-7349
Mohamed El FadiliLIMAS Laboratory, Chemistry Department, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, P.O. Box 1796, Atlas, Fez 30000, Morocco.ORCID 0000-0002-2211-3298
Youssra KanzouaiEngineering Laboratory of Organometallic and Molecular Materials and Environment, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Atlas, Fez 30000, Morocco.ORCID 0009-0004-8902-7484
Somdutt MujwarChitkara College of Pharmacy, Chitkara University, Rajpura 140401, Punjab, India.ORCID 0000-0003-4037-5475
Mohammed M AlanaziDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-0483-8113
Mohammed ChalkhaEngineering Laboratory of Organometallic and Molecular Materials and Environment, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Atlas, Fez 30000, Morocco.ORCID 0000-0002-9400-2183
Asmae NakkabiEngineering Laboratory of Organometallic and Molecular Materials and Environment, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Atlas, Fez 30000, Morocco.
Mohamed BakhouchBioorganic Chemistry Team, Faculty of Science, Chouaïb Doukkali University, P.O. Box 24, El Jadida 24000, Morocco.ORCID 0000-0003-0732-6524
Emese GalResearch Center on Fundamental and Applied Heterochemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany Janos Str., RO-400028 Cluj-Napoca, Romania.ORCID 0000-0003-4324-0787
Luiza Ioana GainaResearch Center on Fundamental and Applied Heterochemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany Janos Str., RO-400028 Cluj-Napoca, Romania.ORCID 0000-0002-1328-0107
Ghali Al HouariEngineering Laboratory of Organometallic and Molecular Materials and Environment, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Atlas, Fez 30000, Morocco.ORCID 0000-0003-1180-9633

Funding

the Researchers Supporting Project number (RSPD2024R628), King Saud University, Riyadh, Saudi Arabia RSPD2024R628
6 · The paper itself

Abstract

Novel isoxazole-triazole conjugates have been efficiently synthesized using 3-formylchromone as starting material according to a multi-step synthetic approach. The structures of the target conjugates and intermediate products were characterized by standard spectroscopic techniques (

Indexed as

Anti-Bacterial AgentsEscherichia coliIsoxazolesMicrobial Sensitivity TestsMolecular Docking SimulationPseudomonas aeruginosaTriazolesComputer SimulationDrug DesignMolecular Dynamics SimulationMolecular StructureStaphylococcus aureusStructure-Activity RelationshipAnti-Bacterial AgentsIsoxazolesTriazolesADMET propertiesantibacterial activitydynamic molecularisoxazolemolecular dockingsynthesistriazole

Identifiers

PMID38893386
PMCPMC11174038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.