ArticleMolecules (Basel, Switzerland)2024
Are Terminal Alkynes Necessary for MAO-A/MAO-B Inhibition? A New Scaffold Is Revealed.
Panagiou Mavroeidi, Leandros P Zorba, Nikolaos V Tzouras, Stavros P Neofotistos, Nikitas Georgiou, Kader Sahin, Murat Şentürk, Serdar Durdagi, Georgios C Vougioukalakis, Thomas Mavromoustakos
Abstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Panagiou MavroeidiLaboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece.
Leandros P ZorbaLaboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece.ORCID 0000-0003-1447-4146 Nikolaos V TzourasLaboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece.
Stavros P NeofotistosLaboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece.ORCID 0000-0002-6083-1872 Nikitas GeorgiouLaboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece.
Kader SahinDepartment of Analytical Chemistry, School of Pharmacy, Bahcesehir University, 34349 Istanbul, Turkey.
Murat ŞentürkDepartment of Biochemistry, Faculty of Pharmacy, Agri Ibrahim Cecen University, 04100 Agri, Turkey.
Serdar DurdagiMolecular Therapy Laboratory, Department of Pharmaceutical Chemistry, School of Pharmacy, Bahcesehir University, 34349 Istanbul, Turkey.
Georgios C VougioukalakisLaboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece.ORCID 0000-0002-4620-5859 Thomas MavromoustakosLaboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece.ORCID 0000-0001-5309-992X Funding
Hellenic Foundation for Research and Innovation 16
6 · The paper itselfAbstract
A versatile family of quaternary propargylamines was synthesized employing the KA
Indexed as
AlkynesMonoamine OxidaseMonoamine Oxidase InhibitorsHumansMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructurePargylinePropylaminesStructure-Activity RelationshipAlkynesMonoamine Oxidasemonoamine oxidase A, humanMonoamine Oxidase InhibitorsPargylinepropargylaminePropylaminesMM/GBSAmolecular dynamicsmonoaminoxidasespropargylamines
Identifiers
PMID38893361
PMCPMC11174103
What OpenQuestion holds
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LicenceCC BY
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